Literature DB >> 26202235

The Epstein-Barr Virus BDLF4 Gene Is Required for Efficient Expression of Viral Late Lytic Genes.

Takahiro Watanabe1, Yohei Narita1, Masahiro Yoshida1, Yoshitaka Sato1, Fumi Goshima1, Hiroshi Kimura1, Takayuki Murata2.   

Abstract

Epstein-Barr virus (EBV) is a gammaherpesvirus, associated with infectious mononucleosis and various types of malignancy. We focused here on the BDLF4 gene of EBV and identified it as a lytic gene, expressed with early kinetics. Viral late gene expression of the BDLF4 knockout strain was severely restricted; this could be restored by an exogenous supply of BDLF4. These results indicate that BDLF4 is important for the EBV lytic replication cycle, especially in late gene expression.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26202235      PMCID： PMC4577904          DOI： 10.1128/JVI.01604-15

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  26 in total

1.  Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis.

Authors:  Moon Jung Song; Seungmin Hwang; Wendy H Wong; Ting-Ting Wu; Sangmi Lee; Hsiang-I Liao; Ren Sun
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-28       Impact factor: 11.205

2.  ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus.

Authors:  Vaithilingaraja Arumugaswami; Ting-Ting Wu; DeeAnn Martinez-Guzman; Qingmei Jia; Hongyu Deng; Nichole Reyes; Ren Sun
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

3.  Identification of Herpes TATT-binding protein.

Authors:  Lucjan S Wyrwicz; Leszek Rychlewski
Journal:  Antiviral Res       Date:  2007-03-28       Impact factor: 5.970

4.  ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68.

Authors:  Ting-Ting Wu; Tina Park; Hana Kim; Thuy Tran; Leming Tong; DeeAnn Martinez-Guzman; Nichole Reyes; Hongyu Deng; Ren Sun
Journal:  J Virol       Date:  2008-12-17       Impact factor: 5.103

5.  A functionally distinct TATA box required for late progression through the Epstein-Barr virus life cycle.

Authors:  T R Serio; N Cahill; M E Prout; G Miller
Journal:  J Virol       Date:  1998-10       Impact factor: 5.103

Review 6.  Epstein-Barr virus: 40 years on.

Authors:  Lawrence S Young; Alan B Rickinson
Journal:  Nat Rev Cancer       Date:  2004-10       Impact factor: 60.716

7.  Murine gammaherpesvirus 68 open reading frame 24 is required for late gene expression after DNA replication.

Authors:  Elaine Wong; Ting-Ting Wu; Nichole Reyes; Hongyu Deng; Ren Sun
Journal:  J Virol       Date:  2007-03-28       Impact factor: 5.103

8.  Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cells.

Authors:  H J Delecluse; T Hilsendegen; D Pich; R Zeidler; W Hammerschmidt
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-07       Impact factor: 11.205

9.  Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts.

Authors:  Hiroki Isomura; Mark F Stinski; Ayumi Kudoh; Takayuki Murata; Sanae Nakayama; Yoshitaka Sato; Satoko Iwahori; Tatsuya Tsurumi
Journal:  J Virol       Date:  2007-12-05       Impact factor: 5.103

10.  Murine gammaherpesvirus 68 open reading frame 31 is required for viral replication.

Authors:  Qingmei Jia; Ting-Ting Wu; Hsiang-I Liao; Vasili Chernishof; Ren Sun
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103
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  16 in total

1.  Comprehensive Analyses of Intraviral Epstein-Barr Virus Protein-Protein Interactions Hint Central Role of BLRF2 in the Tegument Network.

Authors:  Yuya Hara; Takahiro Watanabe; Masahiro Yoshida; H M Abdullah Al Masud; Hiromichi Kato; Tomohiro Kondo; Reiji Suzuki; Shutaro Kurose; Md Kamal Uddin; Masataka Arata; Shouhei Miyagi; Yusuke Yanagi; Yoshitaka Sato; Hiroshi Kimura; Takayuki Murata
Journal:  J Virol       Date:  2022-07-11       Impact factor: 6.549

2.  Lytic Replication and Reactivation from B Cells Is Not Required for Establishing or Maintaining Gammaherpesvirus Latency In Vivo.

Authors:  Arundhati Gupta; Shana M Owens; Darby G Oldenburg; Douglas W White; J Craig Forrest
Journal:  J Virol       Date:  2022-06-01       Impact factor: 6.549

Review 3.  An Epigenetic Journey: Epstein-Barr Virus Transcribes Chromatinized and Subsequently Unchromatinized Templates during Its Lytic Cycle.

Authors:  Adityarup Chakravorty; Bill Sugden; Eric C Johannsen
Journal:  J Virol       Date:  2019-04-03       Impact factor: 5.103

4.  S-Like-Phase Cyclin-Dependent Kinases Stabilize the Epstein-Barr Virus BDLF4 Protein To Temporally Control Late Gene Transcription.

Authors:  Yoshitaka Sato; Takahiro Watanabe; Chihiro Suzuki; Yuichi Abe; H M Abdullah Al Masud; Tomoki Inagaki; Masahiro Yoshida; Takeshi Suzuki; Fumi Goshima; Jun Adachi; Takeshi Tomonaga; Takayuki Murata; Hiroshi Kimura
Journal:  J Virol       Date:  2019-04-03       Impact factor: 5.103

5.  The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex.

Authors:  Jessica McKenzie; Francesc Lopez-Giraldez; Henri-Jacques Delecluse; Ann Walsh; Ayman El-Guindy
Journal:  PLoS Pathog       Date:  2016-11-17       Impact factor: 6.823

6.  The C-Terminus of Epstein-Barr Virus BRRF2 Is Required for its Proper Localization and Efficient Virus Production.

Authors:  Takahiro Watanabe; Keiya Sakaida; Masahiro Yoshida; H M Abdullah Al Masud; Yoshitaka Sato; Fumi Goshima; Hiroshi Kimura; Takayuki Murata
Journal:  Front Microbiol       Date:  2017-01-31       Impact factor: 5.640

7.  Kaposi's sarcoma-associated herpesvirus ORF34 is essential for late gene expression and virus production.

Authors:  Mayu Nishimura; Tadashi Watanabe; Syota Yagi; Takahiro Yamanaka; Masahiro Fujimuro
Journal:  Sci Rep       Date:  2017-03-23       Impact factor: 4.379

8.  An Epstein-Barr Virus-Encoded Protein Complex Requires an Origin of Lytic Replication In Cis to Mediate Late Gene Transcription.

Authors:  Reza Djavadian; Ya-Fang Chiu; Eric Johannsen
Journal:  PLoS Pathog       Date:  2016-06-27       Impact factor: 6.823

Review 9.  Herpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is Key.

Authors:  Henri Gruffat; Roberta Marchione; Evelyne Manet
Journal:  Front Microbiol       Date:  2016-06-06       Impact factor: 5.640

10.  The Epstein-Barr Virus BRRF1 Gene Is Dispensable for Viral Replication in HEK293 cells and Transformation.

Authors:  Masahiro Yoshida; Takahiro Watanabe; Yohei Narita; Yoshitaka Sato; Fumi Goshima; Hiroshi Kimura; Takayuki Murata
Journal:  Sci Rep       Date:  2017-07-20       Impact factor: 4.379
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