Literature DB >> 26198172

Nanocarrier-Integrated Microspheres: Nanogel Tectonic Engineering for Advanced Drug-Delivery Systems.

Yoshiro Tahara1,2, Sada-Atsu Mukai1,2, Shin-Ichi Sawada1,2, Yoshihiro Sasaki1, Kazunari Akiyoshi1,2.   

Abstract

A nanocarrier-integrated bottom-up method is a promising strategy for advanced drug-release systems. Self-assembled nanogels, which are one of the most beneficial nanocarriers for drug-delivery systems, are tectonically integrated to prepare nanogel-crosslinked (NanoClik) microspheres. NanoClik microspheres consisting of nanogel-derived structures (observed by STED microscopy) release "drug-loaded nanogels" after hydrolysis, resulting in successful sustained drug delivery in vivo.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  drug delivery; microspheres; nanogels; polysaccharides; proteins

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Substances：

Year:  2015        PMID： 26198172     DOI： 10.1002/adma.201501557

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  3 in total

1.  Thermosensitive star polymer pompons with a core-arm structure as thermo-responsive controlled release drug carriers.

Authors:  Na Xu; Xiaobei Huang; Guangfu Yin; Meijiao Bu; Ximing Pu; Xianchun Chen; Xiaoming Liao; Zhongbing Huang
Journal:  RSC Adv       Date:  2018-04-25       Impact factor: 4.036

Review 2.  pH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms.

Authors:  Lin Liu; WenDong Yao; YueFeng Rao; XiaoYang Lu; JianQing Gao
Journal:  Drug Deliv       Date:  2017-11       Impact factor: 6.419

3.  Nanogel tectonic porous 3D scaffold for direct reprogramming fibroblasts into osteoblasts and bone regeneration.

Authors:  Yoshiki Sato; Kenta Yamamoto; Satoshi Horiguchi; Yoshiro Tahara; Kei Nakai; Shin-Ichiro Kotani; Fumishige Oseko; Giuseppe Pezzotti; Toshiro Yamamoto; Tsunao Kishida; Narisato Kanamura; Kazunari Akiyoshi; Osam Mazda
Journal:  Sci Rep       Date:  2018-10-25       Impact factor: 4.379
  3 in total

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