Literature DB >> 26197527

Synthesis of Arecatannin A1 from Dimeric Epicatechin Electrophile.

Manato Suda, Kohki Takanashi, Miyuki Katoh, Kiriko Matsumoto, Koichiro Kawaguchi, Sei-ichi Kawahara, Hiroshi Fujii, Hidefumi Makabe.   

Abstract

Synthesis of arrecatannin A1 (1) was accomplished from dimeric epicatechin electrophile, which was prepared by Zn(OTf)2 mediated self-condensation, and monomeric catechin nucleophile. The condensation was successfully worked using Yb(OTf)3 as a Lewis acid in good yield.

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Year:  2015        PMID： 26197527

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN： 1555-9475            Impact factor:   0.986


  2 in total

1.  Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts.

Authors:  Kohki Takanashi; Manato Suda; Kiriko Matsumoto; Chisato Ishihara; Kazuya Toda; Koichiro Kawaguchi; Shogo Senga; Narumi Kobayashi; Mikihiro Ichikawa; Miyuki Katoh; Yasunao Hattori; Sei-Ichi Kawahara; Koji Umezawa; Hiroshi Fujii; Hidefumi Makabe
Journal:  Sci Rep       Date:  2017-08-10       Impact factor: 4.379

2.  Identification and characterization of oligomeric proanthocyanidins with significant anti-cancer activity in adzuki beans (Vigna angularis).

Authors:  Sei-Ichi Kawahara; Chisato Ishihara; Kiriko Matsumoto; Shogo Senga; Koichiro Kawaguchi; Ayaka Yamamoto; Jutalak Suwannachot; Yasunori Hamauzu; Hidefumi Makabe; Hiroshi Fujii
Journal:  Heliyon       Date:  2019-10-23
  2 in total

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