Vassilis Kouloulias1, Sotiria Triantopoulou2, Nikolaos Uzunoglou3, Kyriaki Pistevou-Gompaki4, Alfred Barich5, Anna Zygogianni2, George Kyrgias6, Dimitris Kardamakis7, Dimitris Pectasidis8, John Kouvaris2. 1. 2nd Dept. of Radiology, Attikon University Hospital, Radiotherapy Unit, Athens, Greece. 2. 1st Dept. of Radiology, Attikon University Hospital, Radiotherapy Unit, Athens, Greece. 3. National Technical University of Athens, Greece. 4. Radiotherapy Dept., AHEPA University Hospital, Thessaloniki, Greece. 5. Euromedica Hospital, Thessaloniki, Greece. 6. Radiotherapy Dept., Larisa University Hospital, Larisa, Greece. 7. Radiotherapy Dept., University Hospital, Rion, Patras, Greece. 8. Oncology Dept., Hippokrateion Hospital, Athens, Greece.
Abstract
BACKGROUND: Hyperthermia has been included in the 2013 National Comprehensive Cancer Network (NCCN) guidelines as an option for the treatment of breast recurrences. The purpose of this article is to demonstrate the important role of hyperthermia as a therapeutic modality by presenting clinical trials on this subject carried out in the last decades. MATERIALS AND METHODS: All relevant trials published since 1987 were retrieved from Medline and reviewed. RESULTS: Results show that the addition of hyperthermia to radiotherapy and/or chemotherapy for the treatment of breast cancer enhances treatment response and can increase local control. CONCLUSION: Further studies are required to evaluate potential benefits of hyperthermia in the treatment of other kinds of superficial tumors.
BACKGROUND:Hyperthermia has been included in the 2013 National Comprehensive Cancer Network (NCCN) guidelines as an option for the treatment of breast recurrences. The purpose of this article is to demonstrate the important role of hyperthermia as a therapeutic modality by presenting clinical trials on this subject carried out in the last decades. MATERIALS AND METHODS: All relevant trials published since 1987 were retrieved from Medline and reviewed. RESULTS: Results show that the addition of hyperthermia to radiotherapy and/or chemotherapy for the treatment of breast cancer enhances treatment response and can increase local control. CONCLUSION: Further studies are required to evaluate potential benefits of hyperthermia in the treatment of other kinds of superficial tumors.
Entities:
Keywords:
Breast cancer recurrences; Clinical trials; Hyperthermia; Radiotherapy
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