Literature DB >> 26193945

Effect of rice variety on the physicochemical properties of the modified rice powders and their derived mucoadhesive gels.

Siriporn Okonogi1, Adchareeya Kaewpinta, Sakornrat Khongkhunthian, Songwut Yotsawimonwat.   

Abstract

In the present study; the glutinous Niaw Sanpatong (NSP) and Niaw Koko-6 (NKK), and the non-glutinous Jasmine (JM) and Saohai (SH) were chemically modified. The difference of these rice varieties on the physicochemical characteristics of the modified rice powders and the properties of the derived gels were evaluated. X-ray diffractometer was used for crystalline structure investigation of the rice powders and gels. A parallel plate rheometer was used to measure the rheological property of the gels. It was found that the non-glutinous varieties produced gels with higher mucoadhesive properties than the glutinous rice. Rheological behavior of JM and SH gels was pseudoplastic without yield value whereas that of NSP and NKK gels was plastic with the yield values of 1077.4 ± 185.9 and 536.1 ± 45.8 millipascals-second (mPas), respectively. These different properties are considered to be due to the amylose content in different rice variety. The results suggest that the non-glutinous rice varieties with high amylose content are the most suitable for preparing gels as local delivery systems via the mucosal membrane.

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Year:  2015        PMID: 26193945     DOI: 10.5582/ddt.2015.01009

Source DB:  PubMed          Journal:  Drug Discov Ther        ISSN: 1881-7831


  2 in total

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2.  Preclinical Evaluations of Modified Rice Hydrogel for Topical Ophthalmic Drug Delivery of Praziquantel on Avian Philophalmiasis.

Authors:  Treepecth Prompetch; Akawat Chailorm; Saruda Tiwananthagorn; Nithidol Buranapim; Siriporn Okonogi; Hirotomo Kato; Wasan Katip; Raktham Mektrirat
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  2 in total

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