Literature DB >> 2619289

Chemoattractant activity of Staphylococcus aureus serine proteinase modified human plasma alpha-1-proteinase inhibitor.

K Baran1, M Górka, J Potempa, Z Porwit-Bóbr.   

Abstract

S. aureus serine proteinase inactivates human alpha-1-proteinase inhibitor (alpha-1-PI) by attacking a single peptide bond between Glu354 and Ala355 giving a modified inhibitor which is a tight complex of Mr = 4,000 and 48,000 fragments. In the present paper we show that this proteolytically inactivated alpha-1-PI is a potent chemotactic factor for human neutrophiles at a nanomolar concentration, and we discuss its potential involvement in the inflammatory reaction due to S. aureus infections.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2619289     DOI： 10.1007/bf00443750

Source DB:  PubMed          Journal:  Antonie Van Leeuwenhoek        ISSN： 0003-6072            Impact factor:   2.271


  14 in total

1.  An elastase inhibitor from equine leukocyte cytosol belongs to the serpin superfamily. Further characterization and amino acid sequence of the reactive center.

Authors:  J Potempa; A Dubin; W Watorek; J Travis
Journal:  J Biol Chem       Date:  1988-05-25       Impact factor: 5.157

Review 2.  Methionine sulfoxide and the oxidative regulation of plasma proteinase inhibitors.

Authors:  M W Swaim; S V Pizzo
Journal:  J Leukoc Biol       Date:  1988-04       Impact factor: 4.962

3.  Induction of human neutrophils chemotaxis by staphylococcal lipase.

Authors:  S Tyski; S Tylewska; W Hryniewicz; J Jeljaszewicz
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1987-07

4.  The inactivation of human plasma alpha 1-proteinase inhibitor by proteinases from Staphylococcus aureus.

Authors:  J Potempa; W Watorek; J Travis
Journal:  J Biol Chem       Date:  1986-10-25       Impact factor: 5.157

5.  Plakalbumin, alpha 1-antitrypsin, antithrombin and the mechanism of inflammatory thrombosis.

Authors:  R W Carrell; M C Owen
Journal:  Nature       Date:  1985 Oct 24-30       Impact factor: 49.962

Review 6.  Neutrophil granule constituents and their release in health and disease.

Authors:  L A Boxer; J E Smolen
Journal:  Hematol Oncol Clin North Am       Date:  1988-03       Impact factor: 3.722

Review 7.  Human plasma proteinase inhibitors.

Authors:  J Travis; G S Salvesen
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

8.  Alpha 1-proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase.

Authors:  M J Banda; A G Rice; G L Griffin; R M Senior
Journal:  J Biol Chem       Date:  1988-03-25       Impact factor: 5.157

9.  The inhibitory complex of human alpha 1-proteinase inhibitor and human leukocyte elastase is a neutrophil chemoattractant.

Authors:  M J Banda; A G Rice; G L Griffin; R M Senior
Journal:  J Exp Med       Date:  1988-05-01       Impact factor: 14.307

10.  Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinases.

Authors:  J I Weitz; A J Huang; S L Landman; S C Nicholson; S C Silverstein
Journal:  J Exp Med       Date:  1987-12-01       Impact factor: 14.307
View more
  2 in total

1.  Serine proteinase from Staphylococcus aureus enhances elastin degradation by elastases in the presence of human alpha-1-proteinase inhibitor.

Authors:  D Nowak; J Miedzobrodzki
Journal:  Antonie Van Leeuwenhoek       Date:  1991-02       Impact factor: 2.271

2.  Description of staphylococcus serine protease (ssp) operon in Staphylococcus aureus and nonpolar inactivation of sspA-encoded serine protease.

Authors:  K Rice; R Peralta; D Bast; J de Azavedo; M J McGavin
Journal:  Infect Immun       Date:  2001-01       Impact factor: 3.441
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.