Literature DB >> 26191550

Double clicking for site-specific coupling of multiple enzymes.

Sung In Lim1, Jinhwan Cho, Inchan Kwon.   

Abstract

A method to site-specifically couple multiple enzymes is reported. The approach is based on the site-specific incorporation of a clickable non-natural amino acid into enzymes and two compatible click reactions. The multi-enzyme reaction system exhibited enhanced catalytic efficiency over the respective free enzymes.

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Year:  2015        PMID： 26191550     DOI： 10.1039/c5cc04611d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Controlled Orientation of Active Sites in a Nanostructured Multienzyme Complex.

Authors:  Sung In Lim; Byungseop Yang; Younghan Jung; Jaehyun Cha; Jinhwan Cho; Eun-Sil Choi; Yong Hwan Kim; Inchan Kwon
Journal:  Sci Rep       Date:  2016-12-22       Impact factor: 4.379

2.  Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein.

Authors:  Sung-Tae Yang; Sung In Lim; Volker Kiessling; Inchan Kwon; Lukas K Tamm
Journal:  Sci Rep       Date:  2016-09-08       Impact factor: 4.379

3.  Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide.

Authors:  Mijeong Bak; Junyong Park; Kiyoon Min; Jinhwan Cho; Jihyoun Seong; Young S Hahn; Giyoong Tae; Inchan Kwon
Journal:  Pharmaceutics       Date:  2020-04-16       Impact factor: 6.321
  3 in total

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