Literature DB >> 26190772

Direct Ruthenium-Catalyzed Hydrogenation of Carboxylic Acids to Alcohols.

Xinjiang Cui1, Yuehui Li1, Christoph Topf1, Kathrin Junge1, Matthias Beller2.   

Abstract

The "green" reduction of carboxylic acids to alcohols is a challenging task in organic chemistry. Herein, we describe a general protocol for generation of alcohols by catalytic hydrogenation of carboxylic acids. Key to success is the use of a combination of Ru(acac)3, triphos and Lewis acids. The novel method showed broad substrate tolerance and a variety of aliphatic carboxylic acids including biomass-derived compounds can be smoothly reduced.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  alcohols; carboxylic acids; homogeneous catalysis; hydrogenation; ruthenium

Year:  2015        PMID： 26190772     DOI： 10.1002/anie.201503562

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  10 in total

1.  Catalytic transformation of functionalized carboxylic acids using multifunctional rhenium complexes.

Authors:  Masayuki Naruto; Santosh Agrawal; Katsuaki Toda; Susumu Saito
Journal:  Sci Rep       Date:  2017-06-13       Impact factor: 4.379

2.  Efficient and selective hydrogenation of amides to alcohols and amines using a well-defined manganese-PNN pincer complex.

Authors:  Veronica Papa; Jose R Cabrero-Antonino; Elisabetta Alberico; Anke Spanneberg; Kathrin Junge; Henrik Junge; Matthias Beller
Journal:  Chem Sci       Date:  2017-03-08       Impact factor: 9.825

3.  Hydrogenation of Polyesters to Polyether Polyols.

Authors:  Bernhard M Stadler; Sandra Hinze; Sergey Tin; Johannes G de Vries
Journal:  ChemSusChem       Date:  2019-08-08       Impact factor: 8.928

4.  Facile synthesis of supported Ru-Triphos catalysts for continuous flow application in selective nitrile reduction.

Authors:  Robert Konrath; Frank J L Heutz; Norbert Steinfeldt; Nils Rockstroh; Paul C J Kamer
Journal:  Chem Sci       Date:  2019-07-23       Impact factor: 9.825

5.  Selective catalytic two-step process for ethylene glycol from carbon monoxide.

Authors:  Kaiwu Dong; Saravanakumar Elangovan; Rui Sang; Anke Spannenberg; Ralf Jackstell; Kathrin Junge; Yuehui Li; Matthias Beller
Journal:  Nat Commun       Date:  2016-07-05       Impact factor: 14.919

6.  Cobalt-catalysed reductive C-H alkylation of indoles using carboxylic acids and molecular hydrogen.

Authors:  Jose R Cabrero-Antonino; Rosa Adam; Kathrin Junge; Matthias Beller
Journal:  Chem Sci       Date:  2017-07-26       Impact factor: 9.825

7.  Unprecedented selective homogeneous cobalt-catalysed reductive alkoxylation of cyclic imides under mild conditions.

Authors:  Jose R Cabrero-Antonino; Rosa Adam; Veronica Papa; Mattes Holsten; Kathrin Junge; Matthias Beller
Journal:  Chem Sci       Date:  2017-06-12       Impact factor: 9.825

8.  Biocatalytic Parallel Interconnected Dynamic Asymmetric Disproportionation of α-Substituted Aldehydes: Atom-Efficient Access to Enantiopure (S)-Profens and Profenols.

Authors:  Erika Tassano; Kurt Faber; Mélanie Hall
Journal:  Adv Synth Catal       Date:  2018-06-12       Impact factor: 5.837

9.  Towards a general ruthenium-catalyzed hydrogenation of secondary and tertiary amides to amines.

Authors:  Jose R Cabrero-Antonino; Elisabetta Alberico; Kathrin Junge; Henrik Junge; Matthias Beller
Journal:  Chem Sci       Date:  2016-02-09       Impact factor: 9.825

10.  Highly selective hydrogenation of amides catalysed by a molybdenum pincer complex: scope and mechanism.

Authors:  Thomas Leischner; Lluis Artús Suarez; Anke Spannenberg; Kathrin Junge; Ainara Nova; Matthias Beller
Journal:  Chem Sci       Date:  2019-10-08       Impact factor: 9.825
  10 in total

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