Literature DB >> 26188420

First confirmed case of spondylodiscitis with epidural abscess caused by Parvimonas micra.

Shiro Endo1, Tadanobu Nemoto2, Hisakazu Yano3, Risako Kakuta4, Hajime Kanamori3, Shinya Inomata3, Noriomi Ishibashi3, Tetsuji Aoyagi3, Masumitsu Hatta3, Yoshiaki Gu3, Miho Kitagawa3, Mitsuo Kaku3.   

Abstract

Parvimonas micra was renamed species as within Gram-positive anaerobic cocci and rarely causes severe infections in healthy people. We report the first confirmed case of spondylodiscitis with epidural abscess caused by P. micra in a healthy women. The patient has a pain in low back and anterior left thigh. Magnetic resonance imaging and computed tomography detected the affected lesion at the L2 and L3 vertebral bodies. All isolates from the surgical and needle biopsy specimens were identified as P. micra by 16S rRNA and MALDI-TOF. In this case, P. micra showed high sensitivity to antimicrobial therapy. She was successfully treated with debridement and sulbactam/ampicillin, followed by oral metronidazole for a total of 10 weeks. The causative microorganisms of spondylodiscitis are not often identified, especially anaerobic bacteria tend to be underestimated. On the other hand, antimicrobial therapy for spondylodiscitis is usually prolonged. Accordingly, we emphasize the importance of performing accurate identification including anaerobic bacteria.
Copyright © 2015 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  16S ribosomal RNA; Gram-positive anaerobic cocci; Parvimonas micra; Spondylodiscitis with epidural abscess

Mesh:

Year:  2015        PMID: 26188420     DOI: 10.1016/j.jiac.2015.06.002

Source DB:  PubMed          Journal:  J Infect Chemother        ISSN: 1341-321X            Impact factor:   2.211


  3 in total

1.  Spondylodiscitis due to Parvimonas micra diagnosed by the melting temperature mapping method: a case report.

Authors:  Yoshitsugu Higashi; Shigeki Nakamura; Hideki Niimi; Tomohiro Ueno; Kaoru Matsumoto; Koyomi Kawago; Ippei Sakamaki; Isao Kitajima; Yoshihiro Yamamoto
Journal:  BMC Infect Dis       Date:  2017-08-23       Impact factor: 3.090

2.  Parvimonas micra Spondylodiscitis: A Case Report and Systematic Review of the Literature.

Authors:  D C van Duijvenbode; J W P Kuiper; R M Holewijn; A Stadhouder
Journal:  J Orthop Case Rep       Date:  2018 Sep-Oct

3.  A case of polymicrobial anaerobic spondylodiscitis due to Parvimonas micra and Fusobacterium nucleatum.

Authors:  Leanne M Cleaver; Shara Palanivel; Damien Mack; Simon Warren
Journal:  JMM Case Rep       Date:  2017-04-26
  3 in total

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