| Literature DB >> 26188420 |
Shiro Endo1, Tadanobu Nemoto2, Hisakazu Yano3, Risako Kakuta4, Hajime Kanamori3, Shinya Inomata3, Noriomi Ishibashi3, Tetsuji Aoyagi3, Masumitsu Hatta3, Yoshiaki Gu3, Miho Kitagawa3, Mitsuo Kaku3.
Abstract
Parvimonas micra was renamed species as within Gram-positive anaerobic cocci and rarely causes severe infections in healthy people. We report the first confirmed case of spondylodiscitis with epidural abscess caused by P. micra in a healthy women. The patient has a pain in low back and anterior left thigh. Magnetic resonance imaging and computed tomography detected the affected lesion at the L2 and L3 vertebral bodies. All isolates from the surgical and needle biopsy specimens were identified as P. micra by 16S rRNA and MALDI-TOF. In this case, P. micra showed high sensitivity to antimicrobial therapy. She was successfully treated with debridement and sulbactam/ampicillin, followed by oral metronidazole for a total of 10 weeks. The causative microorganisms of spondylodiscitis are not often identified, especially anaerobic bacteria tend to be underestimated. On the other hand, antimicrobial therapy for spondylodiscitis is usually prolonged. Accordingly, we emphasize the importance of performing accurate identification including anaerobic bacteria.Entities:
Keywords: 16S ribosomal RNA; Gram-positive anaerobic cocci; Parvimonas micra; Spondylodiscitis with epidural abscess
Mesh:
Year: 2015 PMID: 26188420 DOI: 10.1016/j.jiac.2015.06.002
Source DB: PubMed Journal: J Infect Chemother ISSN: 1341-321X Impact factor: 2.211