Literature DB >> 26187259

Exploring the heterogeneity among partially vaccinated children in a population-based cohort.

Christopher A Bell1, Kimberley A Simmonds2, Shannon E MacDonald3.   

Abstract

INTRODUCTION: Vaccination status is often categorized as complete or not-complete. This ignores the potentially important heterogeneity in children whose vaccinations are not-complete. We sought to subcategorize not-completely vaccinated children and determine whether characteristics differed among these subgroups.
METHODS: This retrospective cohort study assessed vaccination status at 2 years of age for 43,965 children in the 2008 Alberta (Canada) birth cohort who were registered with provincial vital statistics records. Children were categorized (based on the five routinely scheduled childhood vaccines) as complete, incomplete, selective, or non-vaccination status. Characteristics derived from administrative health databases were used to determine factors associated with vaccination status.
RESULTS: Population-level vaccination status at 2 years of age was found to be: 71.1% complete and 28.9% not complete (21.9% incomplete, 2.0% selective, and 5.1% non-vaccinated). Midwife delivery at home, compared to physician delivery in hospital, was strongly associated with non-vaccination status (adjusted odds ratio [aOR] 51.70, 95% CI 37.10-72.10). Factors that might pose barriers to vaccination, such as single marital status (aOR 1.58, 95% CI 1.49-1.67), large number of household children (≥4 vs. 1) (aOR 3.24, 95% CI 2.95-3.54), and multiple household moves (≥3 vs. 0) (aOR 1.69, 95% CI 1.35-2.10), were all strongly associated with incomplete vaccination status.
CONCLUSIONS: Of the children who were not completely vaccinated at age 2, the vast majority had started but not completed the vaccination series, while a smaller number were selectively vaccinated or not vaccinated at all. Distinct differences are present among these groups that require attention when addressing vaccine coverage.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Immunization; Incomplete; Partial; Selective status; Vaccination; Vaccine

Mesh:

Substances:

Year:  2015        PMID: 26187259     DOI: 10.1016/j.vaccine.2015.07.004

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  6 in total

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Journal:  Vaccine       Date:  2017-01-17       Impact factor: 3.641

2.  Examination of a prenatal syphilis screening program, Alberta, Canada: 2010-2011.

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3.  Immunization status of children at kindergarten entry in Alberta, Canada.

Authors:  Manisha Dhungana; Matthias Hoben; Celine O'Brien; Shannon E MacDonald
Journal:  Can J Public Health       Date:  2022-07-21

4.  Measuring inequalities in COVID-19 vaccination uptake and intent: results from the Canadian Community Health Survey 2021.

Authors:  Mireille Guay; Aubrey Maquiling; Ruoke Chen; Valérie Lavergne; Donalyne-Joy Baysac; Audrey Racine; Eve Dubé; Shannon E MacDonald; Nicolas L Gilbert
Journal:  BMC Public Health       Date:  2022-09-08       Impact factor: 4.135

5.  Are we speaking the same language? an argument for the consistent use of terminology and definitions for childhood vaccination indicators.

Authors:  Shannon E MacDonald; Margaret L Russell; Xianfang C Liu; Kimberley A Simmonds; Diane L Lorenzetti; Heather Sharpe; Jill Svenson; Lawrence W Svenson
Journal:  Hum Vaccin Immunother       Date:  2018-12-20       Impact factor: 3.452

6.  Measurement of coverage, compliance and determinants of uptake in a publicly funded rotavirus vaccination programme: a retrospective cohort study.

Authors:  Ellen Rafferty; Xiaoyan Guo; Bruce McDonald; Lawrence W Svenson; Shannon Elizabeth MacDonald
Journal:  BMJ Open       Date:  2019-11-02       Impact factor: 2.692

  6 in total

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