| Literature DB >> 26186602 |
Ramasri Sathanoori, Karl Swärd, Björn Olde, David Erlinge.
Abstract
Entities:
Year: 2015 PMID: 26186602 PMCID: PMC4506047 DOI: 10.1371/journal.pone.0133346
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 4Purinergic modulation of high glucose and palmitate-induced IL-6, IL-8 and COX-2 protein.
HUVECs were exposed to high glucose and palmitate (48 h) in the presence or absence of the P2X7 and P2X4 antagonists. The supernatants were analyzed for IL-6 (A) and IL-8 (B) secretion using ELISA. Cell lysates probed for COX-2 (C; 74 kDa) and normalized to β-Tubulin are represented as percentage of control. A representative immunoblot for each protein is depicted. n = 3 to 4 independent experiments each done in replicates; *p ≤ 0.05.