Literature DB >> 26186374

Planned Descemetorhexis Without Endothelial Keratoplasty in Eyes With Fuchs Corneal Endothelial Dystrophy.

Steven B Koenig1.   

Abstract

PURPOSE: The purpose of this study was to describe the results of a simple 6-mm central descemetorhexis in eyes with Fuchs corneal endothelial dystrophy.
METHODS: This prospective nonrandomized IRB approved pilot study was performed on 2 patients with coexisting Fuchs dystrophy and cataract who underwent combined phacoemulsification and descemetorhexis without endothelial transplantation.
RESULTS: In each patient, residual disciform stromal edema corresponded to the diameter of the descemetorhexis and led to an associated loss of visual acuity. Vision improved to 20/40 -1 in case 1 and to 150 -1 in case 2 during a follow-up period of 12 and 10 months, respectively. Endothelial cell repopulation of the descemetorhexis could not be confirmed because of the presence of persistent corneal edema.
CONCLUSIONS: Because of the relatively poor postoperative visual acuity and slow visual recovery, a simple descemetorhexis is not an acceptable form of therapy for eyes with Fuchs corneal endothelial dystrophy.

Entities:  

Mesh:

Year:  2015        PMID: 26186374     DOI: 10.1097/ICO.0000000000000531

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  9 in total

1.  Association of the Gutta-Induced Microenvironment With Corneal Endothelial Cell Behavior and Demise in Fuchs Endothelial Corneal Dystrophy.

Authors:  Viridiana Kocaba; Kishore Reddy Katikireddy; Ilene Gipson; Marianne O Price; Francis W Price; Ula V Jurkunas
Journal:  JAMA Ophthalmol       Date:  2018-08-01       Impact factor: 7.389

2.  Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics.

Authors:  Wei-Ting Ho; Jung-Shen Chang; San-Fang Chou; Wei-Lun Hwang; Po-Jen Shih; Shu-Wen Chang; Muh-Hwa Yang; Tzuu-Shuh Jou; I-Jong Wang
Journal:  J Mol Med (Berl)       Date:  2019-07-13       Impact factor: 4.599

Review 3.  Descemet Stripping Only for a Chronic Descemet Detachment After Cataract Surgery.

Authors:  Kristin E Hirabayashi; David Mark; Jackson Lau; Charles C Lin
Journal:  Cornea       Date:  2020-03       Impact factor: 2.651

4.  A Historical Perspective on Treatment of Fuchs' Endothelial Dystrophy: We have Come a Long Way.

Authors:  Majid Moshirfar; Yanning Ding; Tirth J Shah
Journal:  J Ophthalmic Vis Res       Date:  2018 Jul-Sep

Review 5.  Current Perspectives on Corneal Transplantation (Part 2).

Authors:  Yee Ling Wong; Siyin Liu; Andrew Walkden
Journal:  Clin Ophthalmol       Date:  2022-03-04

6.  Increased Corneal Endothelial Cell Migration in Fuchs Endothelial Corneal Dystrophy: A Live Cell Imaging Study.

Authors:  Stephan Ong Tone; Adam Wylegala; Myriam Böhm; Geetha Melangath; Neha Deshpande; Ula V Jurkunas
Journal:  Ophthalmol Sci       Date:  2021-03-09

Review 7.  Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis.

Authors:  Stephan Ong Tone; Viridiana Kocaba; Myriam Böhm; Adam Wylegala; Tomas L White; Ula V Jurkunas
Journal:  Prog Retin Eye Res       Date:  2020-05-08       Impact factor: 21.198

Review 8.  Regenerative medicine in Fuchs' endothelial corneal dystrophy.

Authors:  Amy E Yuan; Roberto Pineda
Journal:  Taiwan J Ophthalmol       Date:  2020-07-06

Review 9.  New Horizons in the Treatment of Corneal Endothelial Dysfunction.

Authors:  Carlos Rocha-de-Lossada; Rahul Rachwani-Anil; Davide Borroni; José-María Sánchez-González; Raquel Esteves-Marques; Fernando-Luis Soler-Ferrández; Jose-Antonio Gegúndez-Fernández; Vito Romano; Eitan Livny; Marina Rodríguez Calvo-de-Mora
Journal:  J Ophthalmol       Date:  2021-07-09       Impact factor: 1.909

  9 in total

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