Literature DB >> 26186129

Residual immune activation in combined antiretroviral therapy-treated patients with maximally suppressed viremia.

Amélie Guihot1, Chiara Dentone, Lambert Assoumou, Christophe Parizot, Ruxandra Calin, Sophie Seang, Cathia Soulié, Anne-Geneviève Marcelin, Vincent Calvez, Brigitte Autran, Christine Katlama, Dominique Costagliola, Guislaine Carcelain.   

Abstract

Residual immune activation was studied in 51 HIV-infected individuals, 16 with viral load between 1 and 20 copies/ml and 35 with viral load less than 1 copy/ml, and compared with results in 20 healthy blood donors. Higher T-cell activation and IP-10/CXCL10, MIG/CXCL9 and sCD14 plasma levels persisted in both HIV+ groups. The proportion of activated HLA-DR+ CD4 T cells was inversely correlated with the CD4 nadir and the current CD4 cell counts.

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Year:  2016        PMID： 26186129     DOI： 10.1097/QAD.0000000000000815

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  10 in total

Review 1.  Sex Differences in Select Non-communicable HIV-Associated Comorbidities: Exploring the Role of Systemic Immune Activation/Inflammation.

Authors:  Avanthi Raghavan; Dodie E Rimmelin; Kathleen V Fitch; Markella V Zanni
Journal:  Curr HIV/AIDS Rep       Date:  2017-12       Impact factor: 5.071

2.  Rationale and design of the Mechanistic Substudy of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE): Effects of pitavastatin on coronary artery disease and inflammatory biomarkers.

Authors:  Udo Hoffmann; Michael T Lu; Devvora Olalere; Elizabeth C Adami; Michael T Osborne; Alex Ivanov; John Sukumar Aluru; Saeyun Lee; Nadja Arifovic; Edgar Turner Overton; Carl J Fichtenbaum; Judith A Aberg; Beverly Alston-Smith; Karin L Klingman; Myron Waclawiw; Tricia H Burdo; Kenneth C Williams; Markella V Zanni; Patrice Desvigne-Nickens; Katharine Cooper-Arnold; Kathleen V Fitch; Heather Ribaudo; Pamela S Douglas; Steven K Grinspoon
Journal:  Am Heart J       Date:  2019-03-04       Impact factor: 4.749

3.  Sexually transmitted infections and immune activation among HIV-infected but virally suppressed youth on antiretroviral therapy.

Authors:  Tanya L Kowalczyk Mullins; Su X Li; James Bethel; Maureen M Goodenow; Stephanie Hudey; John W Sleasman
Journal:  J Clin Virol       Date:  2018-02-07       Impact factor: 3.168

4.  Evaluation of HIV-DNA and inflammatory markers in HIV-infected individuals with different viral load patterns.

Authors:  Francesca Falasca; Daniele Di Carlo; Corrado De Vito; Isabella Bon; Gabriella d'Ettorre; Alessandra Fantauzzi; Ivano Mezzaroma; Caterina Fimiani; Maria Carla Re; Vincenzo Vullo; Guido Antonelli; Ombretta Turriziani
Journal:  BMC Infect Dis       Date:  2017-08-22       Impact factor: 3.090

5.  Restoring Cytokine Balance in HIV-Positive Individuals with Low CD4 T Cell Counts.

Authors:  Anddre Valdivia; Judy Ly; Leslie Gonzalez; Parveen Hussain; Tommy Saing; Hicret Islamoglu; Daniel Pearce; Cesar Ochoa; Vishwanath Venketaraman
Journal:  AIDS Res Hum Retroviruses       Date:  2017-05-10       Impact factor: 2.205

6.  INSTI-Based Triple Regimens in Treatment-Naïve HIV-Infected Patients Are Associated With HIV-RNA Viral Load Suppression at Ultralow Levels.

Authors:  Sidonie Lambert-Niclot; Anders Boyd; Djeneba Fofana; Nadia Valin; Marc Wirden; Jean-Luc Meynard; Romain Palich; Rachid Agher; Marc-Antoine Valantin; Vincent Calvez; Christine Katlama; Pierre-Marie Girard; Anne-Geneviève Marcelin; Laurence Morand-Joubert
Journal:  Open Forum Infect Dis       Date:  2019-04-10       Impact factor: 3.835

7.  Comparative Transcriptional Analysis Identified Characteristic Genes and Patterns in HIV-Infected Immunological Non-Responders.

Authors:  Xiaosheng Liu; Ling Lin; Lianfeng Lu; Xiaodi Li; Yang Han; Zhifeng Qiu; Xiaoxia Li; Yanling Li; Xiaojing Song; Wei Cao; Taisheng Li
Journal:  Front Immunol       Date:  2022-01-28       Impact factor: 7.561

8.  Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis.

Authors:  Julie Jesson; Siobhan Crichton; Matteo Quartagno; Marcel Yotebieng; Elaine J Abrams; Kulkanya Chokephaibulkit; Sophie Le Coeur; Marie-Hélène Aké-Assi; Kunjal Patel; Jorge Pinto; Mary Paul; Rachel Vreeman; Mary-Ann Davies; Jihane Ben-Farhat; Russell Van Dyke; Ali Judd; Lynne Mofenson; Marissa Vicari; George Seage; Linda-Gail Bekker; Shaffiq Essajee; Diana Gibb; Martina Penazzato; Intira Jeannie Collins; Kara Wools-Kaloustian; Amy Slogrove; Kate Powis; Paige Williams; Mogomotsi Matshaba; Lineo Thahane; Phoebe Nyasulu; Bhekumusa Lukhele; Lumumba Mwita; Adeodata Kekitiinwa-Rukyalekere; Sebastian Wanless; Tessa Goetghebuer; Claire Thorne; Josiane Warszawski; Luisa Galli; Annemarie M C van Rossum; Carlo Giaquinto; Magdalena Marczynska; Laura Marques; Filipa Prata; Luminita Ene; Lyuba Okhonskaya; Marisa Navarro; Antoinette Frick; Lars Naver; Christian Kahlert; Alla Volokha; Elizabeth Chappell; Jean William Pape; Vanessa Rouzier; Adias Marcelin; Regina Succi; Annette H Sohn; Azar Kariminia; Andrew Edmonds; Patricia Lelo; Rita Lyamuya; Edith Apondi Ogalo; Francesca Akoth Odhiambo; Andreas D Haas; Carolyn Bolton; Josephine Muhairwe; Hannock Tweya; Mariam Sylla; Marceline D'Almeida; Lorna Renner; Mark J Abzug; James Oleske; Murli Purswani; Chloe Teasdale; Harriet Nuwagaba-Biribonwoha; Ruth Goodall; Valériane Leroy
Journal:  J Int AIDS Soc       Date:  2022-03       Impact factor: 6.707

9.  Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection.

Authors:  Daniel M Muema; Ngomu A Akilimali; Okechukwu C Ndumnego; Sipho S Rasehlo; Raveshni Durgiah; Doty B A Ojwach; Nasreen Ismail; Mary Dong; Amber Moodley; Krista L Dong; Zaza M Ndhlovu; Jenniffer M Mabuka; Bruce D Walker; Jaclyn K Mann; Thumbi Ndung'u
Journal:  BMC Med       Date:  2020-03-25       Impact factor: 8.775

10.  Inflammatory biomarker levels over 48 weeks with dual vs triple lopinavir/ritonavir-based therapy: Substudy of a randomized trial.

Authors:  Darrell H S Tan; Maria Jose Rolon; Maria Ines Figueroa; Omar Sued; Ana Gun; Rupert Kaul; Janet M Raboud; Leah Szadkowski; Mark W Hull; Sharon L Walmsley; Pedro Cahn
Journal:  PLoS One       Date:  2019-09-06       Impact factor: 3.240
  10 in total

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