Literature DB >> 26186041

A Unified Approach to the Four Azaindoline Families by Inter-/Intramolecular Annulative Diamination of Vinylpyridines.

Michael W Danneman1, Ki Bum Hong1, Jeffrey N Johnston1.   

Abstract

An operationally straightforward and metal-free inter-/intramolecular oxidative diamination of vinyl aminopyridines is a common gateway to access all four azaindoline heterocycle families. 3-Amino azaindolines are formed by the reaction of ortho-vinyl N-tosyl anilines with electron-rich amines using phenyliododiaceate (PIDA) and an iodide additive.

Entities:  

Year:  2015        PMID： 26186041     DOI： 10.1021/acs.orglett.5b01783

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Enantioselective Synthesis of 4- and 6-Azaindolines by a Cation-Directed Cyclization.

Authors:  Alan D Lamb; Peter D Davey; Russell W Driver; Amber L Thompson; Martin D Smith
Journal:  Org Lett       Date:  2016-10-06       Impact factor: 6.005

2.  Hypervalent iodine-mediated Ritter-type amidation of terminal alkenes: The synthesis of isoxazoline and pyrazoline cores.

Authors:  Sang Won Park; Soong-Hyun Kim; Jaeyoung Song; Ga Young Park; Darong Kim; Tae-Gyu Nam; Ki Bum Hong
Journal:  Beilstein J Org Chem       Date:  2018-05-11       Impact factor: 2.883

3.  Enantioselective iodolactonization to prepare ε-lactone rings using hypervalent iodine.

Authors:  Jenna L Payne; Zihang Deng; Andrew L Flach; Jeffrey N Johnston
Journal:  Chem Sci       Date:  2022-06-08       Impact factor: 9.969
  3 in total

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