Literature DB >> 26185370

Current status and progress of pancreatic cancer in China.

Quan-Jun Lin1, Feng Yang1, Chen Jin1, De-Liang Fu1.   

Abstract

Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pancreatic cancer incidence is more significant in the rural areas than in the urban areas. Annual diagnoses and deaths of pancreatic cancer in China are now beyond the number of cases in the United States. GLOBOCAN 2012 estimates that cases in China account for 19.45% (65727/337872) of all newly diagnosed pancreatic cancer and 19.27% (63662/330391) of all deaths from pancreatic cancer worldwide. The population's growing socioeconomic status contributes to the rapid increase of China's proportional contribution to global rates. Here, we present an overview of control programs for pancreatic cancer in China focusing on prevention, early diagnosis and treatment. In addition, we describe key epidemiological, demographic, and socioeconomic differences between China and developed countries. Facts including no nationwide screening program for pancreatic cancer, delay in early detection resulting in a late stage at presentation, lack of awareness of pancreatic cancer in the Chinese population, and low investment compared with other cancer types by government have led to backwardness in China's pancreatic cancer diagnosis and treatment. Finally, we suggest measures to improve health outcomes of pancreatic cancer patients in China.

Entities:  

Keywords:  Diagnosis; Incidence; Pancreatic cancer; Treatment

Mesh:

Year:  2015        PMID: 26185370      PMCID: PMC4499341          DOI: 10.3748/wjg.v21.i26.7988

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  107 in total

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Journal:  Am J Epidemiol       Date:  2009-06-26       Impact factor: 4.897

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Journal:  Gastroenterology       Date:  2007-10-26       Impact factor: 22.682

Review 7.  Breast cancer in China.

Authors:  Lei Fan; Kathrin Strasser-Weippl; Jun-Jie Li; Jessica St Louis; Dianne M Finkelstein; Ke-Da Yu; Wan-Qing Chen; Zhi-Ming Shao; Paul E Goss
Journal:  Lancet Oncol       Date:  2014-06       Impact factor: 41.316

8.  Total laparoscopic pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: oncologic advantages over open approaches?

Authors:  Kristopher P Croome; Michael B Farnell; Florencia G Que; K Marie Reid-Lombardo; Mark J Truty; David M Nagorney; Michael L Kendrick
Journal:  Ann Surg       Date:  2014-10       Impact factor: 12.969

9.  Cigarette smoking, environmental tobacco smoke exposure and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition.

Authors:  Alina Vrieling; H Bas Bueno-de-Mesquita; Hendriek C Boshuizen; Dominique S Michaud; Marianne T Severinsen; Kim Overvad; Anja Olsen; Anne Tjønneland; Françoise Clavel-Chapelon; Marie-Christine Boutron-Ruault; Rudolf Kaaks; Sabine Rohrmann; Heiner Boeing; Ute Nöthlings; Antonia Trichopoulou; Eftihia Moutsiou; Vardis Dilis; Domenico Palli; Vittorio Krogh; Salvatore Panico; Rosario Tumino; Paolo Vineis; Carla H van Gils; Petra H M Peeters; Eiliv Lund; Inger T Gram; Laudina Rodríguez; Antonio Agudo; Nerea Larrañaga; María-José Sánchez; Carmen Navarro; Aurelio Barricarte; Jonas Manjer; Björn Lindkvist; Malin Sund; Weimin Ye; Sheila Bingham; Kay-Tee Khaw; Andrew Roddam; Tim Key; Paolo Boffetta; Eric J Duell; Mazda Jenab; Valentina Gallo; Elio Riboli
Journal:  Int J Cancer       Date:  2010-05-15       Impact factor: 7.396

10.  Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis.

Authors:  J Everhart; D Wright
Journal:  JAMA       Date:  1995 May 24-31       Impact factor: 56.272

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  108 in total

1.  The lncRNA-HOXA-AS2/EZH2/LSD1 oncogene complex promotes cell proliferation in pancreatic cancer.

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2.  Pancreatic cancer incidence trends: evidence from the Surveillance, Epidemiology and End Results (SEER) population-based data.

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Journal:  Int J Epidemiol       Date:  2018-04-01       Impact factor: 7.196

3.  Inhibition of LINC00994 represses malignant behaviors of pancreatic cancer cells: interacting with miR-765-3p/RUNX2 axis.

Authors:  Xuan Zhu; Xing Niu; Chunlin Ge
Journal:  Cancer Biol Ther       Date:  2019-02-11       Impact factor: 4.742

4.  miR-128 induces pancreas cancer cell apoptosis by targeting MDM4.

Authors:  Hongchao Han; Lisheng Wang; Jie Xu; Aikun Wang
Journal:  Exp Ther Med       Date:  2018-04-10       Impact factor: 2.447

5.  Pancreatectomy with Hepatic Artery Resection for Pancreatic Head Cancer.

Authors:  Feng Yang; Xiaoyi Wang; Chen Jin; Hang He; Deliang Fu
Journal:  World J Surg       Date:  2019-11       Impact factor: 3.352

Review 6.  Recent advances in research on aspartate β-hydroxylase (ASPH) in pancreatic cancer: A brief update.

Authors:  Guofang Hou; Boran Xu; Yanghui Bi; Chuanlin Wu; Beibei Ru; Bei Sun; Xuewei Bai
Journal:  Bosn J Basic Med Sci       Date:  2018-11-05       Impact factor: 3.363

7.  microRNA-1225 inhibit apoptosis of pancreatic cancer cells via targeting JAK1.

Authors:  Ruolei Zhong; Sheng Li; Kaifeng Fang; Liu Yang; Li Wang
Journal:  Cell Cycle       Date:  2019-04-24       Impact factor: 4.534

8.  Curcumin inhibits cell growth and invasion and induces apoptosis through down-regulation of Skp2 in pancreatic cancer cells.

Authors:  Jingna Su; Xiuxia Zhou; Lixia Wang; Xuyuan Yin; Zhiwei Wang
Journal:  Am J Cancer Res       Date:  2016-09-01       Impact factor: 6.166

9.  The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma.

Authors:  Ling Ma; Xiaodong Tian; Feng Wang; Zhengkui Zhang; Chong Du; Xuehai Xie; Marko Kornmann; Yinmo Yang
Journal:  Cancer Biol Ther       Date:  2016-08-29       Impact factor: 4.742

10.  Association between small intestinal bacterial overgrowth and toll-like receptor 4 in patients with pancreatic carcinoma and cholangiocarcinoma.

Authors:  Xiaoying Ma; Heju Wang; Peng Zhang; Lin Xu; Zibin Tian
Journal:  Turk J Gastroenterol       Date:  2019-02       Impact factor: 1.852

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