Literature DB >> 26184493

Towards host-directed therapies for tuberculosis.

Alimuddin Zumla1, Markus Maeurer2, Jeremiah Chakaya3, Michael Hoelscher4, Francine Ntoumi5, Roxana Rustomjee6, Cristina Vilaplana7, Dorothy Yeboah-Manu8, Voahangy Rasolof9, Paula Munderi10, Nalini Singh11, Eleni Aklillu12, Nesri Padayatchi13, Eusebio Macete14, Nathan Kapata15, Modest Mulenga16, Gibson Kibiki17, Sayoki Mfinanga18, Thomas Nyirenda19, Leonard Maboko20, Alberto Garcia-Basteiro14, Niaina Rakotosamimanana9, Matthew Bates15, Peter Mwaba15, Klaus Reither21, Sebastien Gagneux21, Sarah Edwards22, Elirehema Mfinanga23, Salim Abdulla24, Pere-Joan Cardona7, James B W Russell25, Vanya Gant26, Mahdad Noursadeghi1, Paul Elkington27, Maryline Bonnet28, Clara Menendez29, Tandakha N Dieye30, Bassirou Diarra31, Almoustapha Maiga31, Abraham Aseffa32, Shreemanta Parida2, Christian Wejse33, Eskild Petersen33, Pontiano Kaleebu10, Matt Oliver34, Gill Craig35, Tumena Corrah36, Leopold Tientcheu37, Martin Antonio37, Martin Rao2, Timothy D McHugh38, Aziz Sheikh39, Giuseppe Ippolito40, Gita Ramjee41, Stefan H E Kaufmann42, Gavin Churchyard43, Andrie Steyn44, Martin Grobusch45, Ian Sanne46, Neil Martinson47, Rajhmun Madansein48, Robert J Wilkinson49, Bongani Mayosi50, Marco Schito51, Robert S Wallis43.   

Abstract

The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjunct host-directed therapies.

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Year:  2015        PMID: 26184493     DOI: 10.1038/nrd4696

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  5 in total

Review 1.  Advances in the development of new tuberculosis drugs and treatment regimens.

Authors:  Alimuddin Zumla; Payam Nahid; Stewart T Cole
Journal:  Nat Rev Drug Discov       Date:  2013-05       Impact factor: 84.694

Review 2.  Tuberculosis treatment and management--an update on treatment regimens, trials, new drugs, and adjunct therapies.

Authors:  Alimuddin Zumla; Jeremiah Chakaya; Rosella Centis; Lia D'Ambrosio; Peter Mwaba; Matthew Bates; Nathan Kapata; Thomas Nyirenda; Duncan Chanda; Sayoki Mfinanga; Michael Hoelscher; Markus Maeurer; Giovanni Battista Migliori
Journal:  Lancet Respir Med       Date:  2015-03-09       Impact factor: 30.700

Review 3.  Autophagy in the fight against tuberculosis.

Authors:  Carla F Bento; Nuno Empadinhas; Vítor Mendes
Journal:  DNA Cell Biol       Date:  2015-01-21       Impact factor: 3.311

Review 4.  Advancing host-directed therapy for tuberculosis.

Authors:  Robert S Wallis; Richard Hafner
Journal:  Nat Rev Immunol       Date:  2015-03-13       Impact factor: 53.106

5.  Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.

Authors:  Sarah A Stanley; Amy K Barczak; Melanie R Silvis; Samantha S Luo; Kimberly Sogi; Martha Vokes; Mark-Anthony Bray; Anne E Carpenter; Christopher B Moore; Noman Siddiqi; Eric J Rubin; Deborah T Hung
Journal:  PLoS Pathog       Date:  2014-02-20       Impact factor: 6.823

  5 in total
  46 in total

1.  Translating the Tuberculosis Research Agenda: Much Accomplished, but Much More to Be Done.

Authors:  Marco Schito; Markus Maeurer; Peter Kim; Debra Hanna; Alimuddin Zumla
Journal:  Clin Infect Dis       Date:  2015-10-15       Impact factor: 9.079

Review 2.  Update in Mycobacterium tuberculosis lung disease 2014.

Authors:  Paul Elkington; Alimuddin Zumla
Journal:  Am J Respir Crit Care Med       Date:  2015-10-01       Impact factor: 21.405

Review 3.  [Drug-resistant tuberculosis. Epidemiology, diagnostics and therapy].

Authors:  M P Grobusch; F Schaumburg; E Altpeter; S Bélard
Journal:  Internist (Berl)       Date:  2016-02       Impact factor: 0.743

4.  Gene Expression Signatures in Tuberculosis Have Greater Overlap with Autoimmune Diseases Than with Infectious Diseases.

Authors:  Kalum Clayton; Marta E Polak; Christopher H Woelk; Paul Elkington
Journal:  Am J Respir Crit Care Med       Date:  2017-09-01       Impact factor: 21.405

5.  Metformin Adjunctive Therapy Does Not Improve the Sterilizing Activity of the First-Line Antitubercular Regimen in Mice.

Authors:  Noton K Dutta; Michael L Pinn; Petros C Karakousis
Journal:  Antimicrob Agents Chemother       Date:  2017-07-25       Impact factor: 5.191

Review 6.  The Goldilocks model of immune symbiosis with Mycobacteria and Candida colonizers.

Authors:  Richard T Robinson; Anna R Huppler
Journal:  Cytokine       Date:  2017-05-29       Impact factor: 3.861

7.  Anti-infective Activity of 2-Cyano-3-Acrylamide Inhibitors with Improved Drug-Like Properties against Two Intracellular Pathogens.

Authors:  Karla D Passalacqua; Marie-Eve Charbonneau; Nicholas J Donato; Hollis D Showalter; Duxin Sun; Bo Wen; Miao He; Hanshi Sun; Mary X D O'Riordan; Christiane E Wobus
Journal:  Antimicrob Agents Chemother       Date:  2016-06-20       Impact factor: 5.191

Review 8.  Inhibiting Mycobacterium tuberculosis within and without.

Authors:  Stewart T Cole
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2016-11-05       Impact factor: 6.237

9.  Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis.

Authors:  Andre Kubler; Christer Larsson; Brian Luna; Bruno B Andrade; Eduardo P Amaral; Michael Urbanowski; Marlene Orandle; Kevin Bock; Nicole C Ammerman; Laurene S Cheung; Kathryn Winglee; Marc Halushka; Jin Kyun Park; Alan Sher; Jon S Friedland; Paul T Elkington; William R Bishai
Journal:  J Infect Dis       Date:  2015-09-27       Impact factor: 5.226

10.  Broad Anti-Viral Capacities of Lian-Hua-Qing-Wen Capsule and Jin-Hua-Qing-Gan Granule and Rational use Against COVID-19 Based on Literature Mining.

Authors:  Mingfei Shi; Bo Peng; An Li; Ziyun Li; Ping Song; Jing Li; Ruodan Xu; Ning Li
Journal:  Front Pharmacol       Date:  2021-05-14       Impact factor: 5.810

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