Angiosarcoma involving colon and bone successfully responded to paclitaxel and zoledronate: case report.

Angiosarcoma involving the gastrointestinal tract is extremely rare. We present a case of multifocal angiosarcoma involving the colon and bone. A 73-year-old male presented with anemia and pain in the left supra-iliac lesion. Colonoscopy revealed multiple hemorrhagic-appearance tumors. Computed tomography scan showed masses in the sigmoid colon and bone. A left-sided colectomy was performed to prevent bleeding from the tumor. The histopathological diagnosis was angiosarcoma of multiple sites of the colon. We chose a combination of paclitaxel and zoledronate as the chemotherapy regimen. After surgery, bone lesions were diminished by chemotherapy and showed no uptake on (18)F-fluorodeoxyglucose-positron emission tomography. The patient survived for 38 months after surgery.