| Literature DB >> 26180502 |
Saurabh Rohatgi1, Nikhil H Ramaiya1, Jyothi P Jagannathan1, Stephanie A Howard1, Atul B Shinagare1, Katherine M Krajewski1.
Abstract
Chordomas are rare malignant bone tumours with a predilection for the axial skeleton, especially the sacrum and skull base. Median survival in patients with metastatic disease is usually dismal. Treatment is challenging due to the propensity for local recurrence, metastatic disease as well as lack of clear consensus regarding the optimal management. Our case report highlights two cases of sacral chordoma with locally recurrent and widespread metastatic disease, stable on molecular targeted therapy.Entities:
Keywords: Chordoma; Kordoma; imatinib; metastasis; metastaz; positron emission tomography; pozitron emisyon tomografi
Year: 2015 PMID: 26180502 PMCID: PMC4494552 DOI: 10.5152/eurasianjmed.2015.52
Source DB: PubMed Journal: Eurasian J Med ISSN: 1308-8734