Effects of a multifactorial fall prevention program on balance, gait, and fear of falling in post-stroke inpatients.

[Purpose] This study investigated the effects of a multifactorial fall prevention program on balance, gait, and fear of falling in stroke patients. [Subjects] Twenty-five stroke patients were divided randomly into multifactorial fall prevention program group (n=15) and control treadmill group (n=10). [Methods] All interventions were applied for 30 min, five times per week, for five weeks. The fall prevention program included interventions based on the "Step Up to Stop Falls" initiative and educational interventions based on the Department of Health guidelines. For those in the treadmill group, the speed was increased gradually. The Korean falls efficacy scale and Korean activities-specific balance confidence scale were used to assess fear of falling. To assess balance and walking ability, the Korean performance-oriented mobility assessment scale and the 10-m and 6-minute walk tests were used.
[Results] The fall prevention program interventions were found to be very effective at improving gait, balance, and fear of falling compared with the treadmill intervention and therefore seem appropriate for stroke patients.
[Conclusion] A multifactorial fall prevention program is effective at improving balance, gait ability, and fear of falling. It is a more specific and broad intervention for reducing falls among inpatients in facilities and hospitals.

RCT Entities:   Population Interventions Outcomes

INTRODUCTION

Stroke manifestations vary depending on the lesion site and severity. Development of hemiplegia causes difficulties in weight bearing on the affected side and maintaining balance, both of which are required for correct posture. An imbalanced posture results in instability during standing, muscle weakness, and a limited range of motion. These features are predictive of an increased likelihood of falls and decreased gait ability1). The risk of falls may increase after a patient has experienced one fall, even in the absence of physical damage, because of an increased fear of falling2). Schoenfelder et al. suggested that fall prevention education and muscle strengthening can decrease the fear of falling and risk of falls3). A fall prevention program that includes balance, muscle strengthening, and flexibility training is effective for improving gait, balance ability, and perception of the risk of falling4). Because falls have multiple causes, multifactorial interventions including patient education and improvement of muscle strength, balance, and gait are required for fall prevention. However, most fall prevention programs consist of a single item, and because falls are influenced by physical, psychological, environmental, and social factors, an effective fall prevention program would include exercise and educational interventions5). Although many studies have reported ways to prevent falls6, 7), the subjects in these investigations were elderly people in the community, and only a single program was applied. Fall prevention interventions have to begin in high-risk facilities and hospitals8). Therefore, the purpose of this study was to study baseline data and decrease the risk of falls using a multifactorial fall prevention program (MFPP) in post-stroke patients.

SUBJECTS AND METHODS

Thirty patients (16 males, 14 females) who had experienced a stroke within the previous year at the M hospital in Seoul-Si were included. Based on previous studies, the following inclusion criteria were used: age <65 years, able to walk independently, Korean mini-mental state examination (MMSE-K) score >24, and able to understand the study procedures and communicate9). The exclusion criteria were medication use, which can influence gait ability and balance, visual deficits, and vestibular impairment. This study used a randomized two-group pretest-posttest design. Subjects were randomly allocated to the MFPP group (n=15, MFPG) or treadmill exercise group (n=15, TEG). Five patients were excluded from the MFPG. From the TEG, 1 male and 3 female patients were excluded due to discharge before completion of the experiment, and 1 female patient was excluded for personal reasons. The randomization was generated by a computer drawing lots. All study procedures were explained to the subjects prior to participation, and written informed consent was obtained from all subjects. This study was approved by the Sahmyook University Institutional Review Board.

Before the intervention program, the subjects’ gait speed and endurance were assessed using the Korean performance-oriented motor assessment (POMA-K) scale10), 10-m walk test, and 6-min walk test. The Korean falls efficacy scale11) (FES-K) and Korean activities-specific balance confidence12) (ABC-K) scale were used to assess the balance self-assurance of the patients. The multifactorial exercise program included education regarding fall prevention, neuro-developmental treatment (NDT), and training for muscle strengthening, balance, and flexibility. It was carried out for 30 min per day, five times a week, over a 5-week period. The treadmill exercise program included NDT and treadmill exercise, with a 0.4 km/h increase in speed per week. The details of both exercise programs are described in Tables 1 and 2.

Table 1.

Multifactorial fall prevention program

Exercise type			Time (sets/duration)
Exercise	Strengthening intervention	Calf stretching	30–60 sec 5 repetitions
		Heel/Toe raise	5–10 sec
		Marching	Floor/Stairs
		SLR: forward, side, backward	5–10 sec, 10 repetitions, 3 sets
		Leg curl	In sitting on chair
	Balance intervention	Ankle ROM exercise	Draw A to Z
		Standing on air cushion	Up and down the leg alternately
		Diagonal movement exercise	In holding both hands with trunk rotation
	Flexibility intervention	Standing with head movement	General standing 30 sec Tandem standing 30 sec
		Standing on balance pad	Eye open/close
Education	Regulation of fall Environmental factor	Before starting exercise for 5 minutes
General physical therapy	NDTPNF	General stretching and strengtheningStatic and dynamic balance training	2 times/day, 5 days/week

ROM: range of motion; SLR: straight leg raise; NDT: neurodevelopmental technique; PNF: proprioceptive neuromuscular facilitation

Table 2.

Treadmill exercise program

Exercise	Treadmill	Increase the speed by 0.4 km/h per weekf possible independent walking	Exercise stopped in cases of fatigue,dyspnea on exertion, or on patients’ request
General physical therapy	NDTPNF	General stretching and strengtheningStatic and dynamic balance training	2 times/day, 5 days/week

NDT: neurodevelopmental technique; PNF: proprioceptive neuromuscular facilitation

The SPSS version 19.0 statistical software was used for all analyses. Statistics were used to describe patient characteristics after confirming that the data were normally distributed. A comparison of the general characteristics was performed using the independent t-test or χ2 test. Pre- and post-data were analyzed using the paired t-test to test differences within the groups. Scheffé’s post-hoc test was used to test the significance of differences between the groups. A significance level of 0.05 was used for all measurements.

RESULTS

The general characteristics of the subjects are presented in Table 3. No significant differences in general characteristics were observed between the MFPG and TEG (age, 49.9 years vs. 53.2 years; height, 168.1 cm vs. 164.8 cm; body weight, 64.7 kg vs. 62.3 kg).

Table 3.

General characteristics

Parameter	MFPG	TEG
Gender Male/Female (%)	10/5 (66.7/33.3)	5/5 (50.0/50.0)
Age, years	47.9±10.6	53.2±12.3
Height, cm	165.1±7.7	164.8±10.8
Weight, kg	64.7±8.4	62.3±8.4
Disease cause Infarction /Hemorrhage	8/7 (53.3/46.7)	5/5 (50.0/50.0)
Affected side Right/Left (%)	10/5 (66.7/33.3)	4/6 (40.0/60.0)
Disease duration (months)	8.02±2.9	6.22±2.2
MMSE-K	26.7±2.3	26.3±1.8

Values are expressed as n (%) or mean±SD. MFPG: multifactorial program group; TEG: treadmill exercise group; MMSE-K: mini-mental state examination-Korean

Differences in pre- and post-test values within and between the groups are summarized in Table 4. The POMA-K scores were significantly higher in the MFPG (p<0.01) and significantly different between the groups (p<0.05). Both groups showed significant improvements in the 10-m walk test (MFPG, p<0.01; TEG, p<0.05) and gait speed, but there was no difference between the groups. The MFPG showed a significant improvement in the 6-min walk test score (p<0.001), and the difference was significantly greater than that in the TEG. In addition, the FES-K score significantly improved in the MFPG only (p<0.05), with a significant difference between groups (p<0.05). The ABC-K score either (p<0.05).

Table 4.

Comparison of POMA-K, 10-m walk test, 6-minute walk test, FES-K, and ABC scale-K

	MFPG (n=15)		TEG (n=10)
	Pretest	Posttest	Pretest	Posttest
POMA-K	19.67 (6.04)	23.80 (5.17)**	17.30 (4.24)	17.40 (5.58)
10-m walk test (m/s)	0.48 (0.23)	0.65 (0.28)**	0.43 (0.26)	0.55 (0.29)*
6-minute walk test (m/s)	0.49 (0.25)	0.60 (0.26)**	0.40 (0.23)	0.44 (0.27)
FES-K	59.00 (21.03)	72.93 (15.61)**	57.30 (19.32)	55.50 (25.67)
ABC scale-K	47.35 (18.14)	62.40 (17.28)**	39.45 (19.78)	40.70 (25.50)

Values are expressed as mean (SD). Within group differences *p<0.05, **p<0.01. MFPG: multifactorial program group; TEG: treadmill exercise group; POMA-K: performance-oriented motor assessment-Korean; FES-K: fall efficacy scale-Korean; ABC scale-K: activities-specific balance confidence scale-Korean

DISCUSSION

This study aimed to investigate the effects of an MFPP comprised of exercise and educational interventions for improving balance, gait, as well as fear of falling, and to provide a suitable approach for use of a fall prevention program in stroke inpatients. Guidelines for fall prevention in the United States and Britain suggest that a multifactorial program, involving exercise and educational interventions, is more effective than a single intervention, and that fall prevention programs have to be focused on physiological and psychological factors such as fear of falling5). Because exercise interventions alone cannot improve FES scores, exercise and educational intervention are needed for individuals at a high risk for falls3). Tinetti studied the benefits of multifactorial interventions for muscle strengthening and improvement of balance and self-confidence in comparison to those of a single intervention. They recommend an MFPP, because physical and occupational therapists alone cannot control falls or reduce the fear of falling13).

In this study, the MFPG showed significant improvements in physical activity and FES-K scores, as shown in other studies4, 13, 14). The POMA-K scale score, which is focused on mobility, significantly increased in the MFPG (p<0.01), and this result indicates a greater increase than that seen in previous studies15). For gait ability, the 10-m walk test and 6-min walk test were used in this study. The MFPG had a significantly increased 10-m walk test score (p<0.01) and 6-min walk test score (p<0.01), but the TEG showed a significant increase only in the 10-m walk test score (p<0.05). Because fall prevention exercise interventions increase balance ability and strengthen muscles, the risk of falls is decreased by 15–20%16). In particular, the 6-min walk test score, used to assess functional capacity in older adults17), significantly increased in the MFPG. Therefore, it can be seen that an MFPP positively influences walking ability and aerobic capacity.

Batchelor et al. suggested that an MFPP improves balance (p<0.01), gait speed (p<0.01), and the FES score (p<0.05) in stroke patients returning home after rehabilitation18). Their results show that exercise and educational interventions have to be used together to reduce the fear of falling. Our study demonstrates that an MFPP was effective at improving FES-K scores (p<0.05), and the treadmill exercise was not (p>0.05). In addition, the FES-K score was significantly different between the groups (p<0.05). The ABC-K scale, a more objective evaluation of the fear of falling, showed the same results as the FES-K (MFPG p<0.01, TEG p>0.05). In other words, exercise intervention improved balance and gait ability, and educational intervention improved the psychological aspect of the fear of falling. Cumming et al. reported that home visits can prevent falls among older people who are at increased risk of falling. However, this effect may not be the result of improved balance and strength alone, but also due to a decreased fear of falling8). The risk of falling within 12 months in those with a decreased FES score was half that in patients whose FES score had not decreased9). Therefore, interventions for fall prevention need to begin at hospital facilities, and programs must consist of a variety of approaches. Using the ABC-K scale with the FES scale is an efficient method of evaluating the fear of outdoor activities as well as indoor activities18).

While this study demonstrates the effectiveness of an MFPP, it has some limitations. First, although balance, gait ability and FES scores significantly improved after the MFPP, it can be difficult to prove the frequency of falls using these factors alone; the validity of this study is therefore limited. Second, a reduction in fall frequency is the eventual goal, but an intervention period of 5 weeks is too short to allow an assessment of this factor. It is therefore suggested that further studies include longer intervention and follow-up periods.