Literature DB >> 26178707

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Jeffrey S Pawlikowski, Claire Brock, Sheau-Chiann Chen, Lara Al-Olabi, Colin Nixon, Fiona McGregor, Simon Paine, Estelle Chanudet, Wendy Lambie, William M Holmes, James M Mullin, Ann Richmond, Hong Wu, Karen Blyth, Ayala King, Veronica A Kinsler, Peter D Adams.   

Abstract

Entities:  

Year:  2015        PMID： 26178707     DOI： 10.1038/jid.2015.230

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


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  3 in total

1.  Treatment for giant congenital nevi moves a step closer.

Authors:  Joanna Pozniak; Jean-Christophe Marine
Journal:  Cell Res       Date:  2022-09       Impact factor: 46.297

2.  Topical therapy for regression and melanoma prevention of congenital giant nevi.

Authors:  Yeon Sook Choi; Tal H Erlich; Max von Franque; Inbal Rachmin; Jessica L Flesher; Erik B Schiferle; Yi Zhang; Marcello Pereira da Silva; Alva Jiang; Allison S Dobry; Mack Su; Sharon Germana; Sebastian Lacher; Orly Freund; Ezra Feder; Jose L Cortez; Suyeon Ryu; Tamar Babila Propp; Yedidyah Leo Samuels; Labib R Zakka; Marjan Azin; Christin E Burd; Norman E Sharpless; X Shirley Liu; Clifford Meyer; William Gerald Austen; Branko Bojovic; Curtis L Cetrulo; Martin C Mihm; Dave S Hoon; Shadmehr Demehri; Elena B Hawryluk; David E Fisher
Journal:  Cell       Date:  2022-05-12       Impact factor: 66.850

3.  MEK inhibition appears to improve symptom control in primary NRAS-driven CNS melanoma in children.

Authors:  Veronica A Kinsler; Patricia O'Hare; Thomas Jacques; Darren Hargrave; Olga Slater
Journal:  Br J Cancer       Date:  2017-03-02       Impact factor: 7.640
  3 in total

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