Literature DB >> 26178516

[Treatment of trigeminal neuralgia: an update and future prospects of percutaneous techniques].

Agustín Bescós1, Vicenç Pascual, Marcos Escosa-Bage, Xavier Malaga.   

Abstract

INTRODUCTION: Trigeminal neuralgia is one of the most severe facial pain syndromes. The annual incidence varies between 4-13% and has a significant effect on patients' quality of life. When the pain cannot be controlled by pharmacological treatment, several different surgical options can be considered. The choice of technique will be based on observational studies and its application depends on the experience of each centre. AIMS: To assess the effectiveness and level of evidence of pharmacological and surgical treatment in trigeminal neuralgia, and to analyse the current role of percutaneous techniques in the treatment of this pathology. DEVELOPMENT: The initial treatment of trigeminal neuralgia is pharmacological and carbamazepine is the only drug with a sufficiently high level of evidence. The percutaneous surgical techniques are effective and easy to apply, but the tendency for relapses to appear means there is a preference for vascular microdecompression. Yet, there are no reports of comparative studies that determine the superiority of a technique with a good level of evidence. The three most commonly used percutaneous techniques, balloon compression, glycerol rhizotomy and thermocoagulation by radiofrequency, were reviewed. This last technique is the one that has undergone the greatest development in recent years, with the emergence of neurophysiological techniques that make it possible to optimise results.
CONCLUSIONS: The selection of a surgical technique for use in trigeminal neuralgia does not have much backing from randomised clinical trials. The new procedures in the application of radiofrequency can improve the treatment prospects of this pathology.

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Year:  2015        PMID: 26178516

Source DB:  PubMed          Journal:  Rev Neurol        ISSN: 0210-0010            Impact factor:   0.870


  3 in total

1.  Continuous Intra-Arterial Blood Pressure Monitoring Improves the Efficiency of Percutaneous Balloon Compression of the Trigeminal Ganglion for Trigeminal Neuralgia.

Authors:  Yuchao Zuo; Dengpan Song; Yan Hu; Shengqi Zhao; Mingchu Zhang; Meng Wang; Fuyou Guo
Journal:  Pain Res Manag       Date:  2022-10-03       Impact factor: 2.667

2.  Abnormal brain white matter in patients with right trigeminal neuralgia: a diffusion tensor imaging study.

Authors:  Junpeng Liu; Jiajia Zhu; Fei Yuan; Xuejun Zhang; Quan Zhang
Journal:  J Headache Pain       Date:  2018-06-22       Impact factor: 7.277

3.  Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments.

Authors:  Eder Gambeta; Juliana G Chichorro; Gerald W. Zamponi
Journal:  Mol Pain       Date:  2020 Jan-Dec       Impact factor: 3.395

  3 in total

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