Literature DB >> 26177996

Subcutaneous fat necrosis causing neonatal hypercalcaemia.

Emma Tuddenham1, Arun Kumar2, Anne Tarn1.   

Abstract

Hypercalcaemia in neonates is rare and often asymptomatic, but can have significant morbidity. If severe, it can cause symptoms including irritability, vomiting and seizures. We present the case of a baby girl, born at term after a traumatic delivery, who developed severe hypercalcaemia with nephrocalcinosis. She had several large areas of subcutaneous fat necrosis following delivery, with prolonged low-level elevation of C reactive protein. Subcutaneous fat necrosis of the newborn is a rare and underdiagnosed condition, often accompanied by high plasma calcium. Although self-limiting, it is important to recognise and treat this condition to minimise kidney damage, and to avoid unnecessary investigations or treatment with long courses of antibiotics. The infant recovered well, although a degree of nephrocalcinosis remains. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26177996      PMCID: PMC4513574          DOI: 10.1136/bcr-2014-208460

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

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Journal:  Pediatr Nephrol       Date:  1999-08       Impact factor: 3.714

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Journal:  J Pediatr       Date:  1997-08       Impact factor: 4.406

Review 3.  Subcutaneous fat necrosis of the newborn: a review of 11 cases.

Authors:  A D Burden; B R Krafchik
Journal:  Pediatr Dermatol       Date:  1999 Sep-Oct       Impact factor: 1.588

4.  Subcutaneous fat necrosis of the newborn: a systematic evaluation of risk factors, clinical manifestations, complications and outcome of 16 children.

Authors:  E Mahé; N Girszyn; S Hadj-Rabia; C Bodemer; D Hamel-Teillac; Y De Prost
Journal:  Br J Dermatol       Date:  2007-04       Impact factor: 9.302

5.  Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report.

Authors:  G Lombardi; R Cabano; L Bollani; C Del Forno; M Stronati
Journal:  Eur J Pediatr       Date:  2008-08-23       Impact factor: 3.183

  5 in total
  4 in total

1.  The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion.

Authors:  Saime Ergen Dibeklioğlu; Veysel Nijat Baş; Emine Esin Yalınbaş; Sermin Tok Umay
Journal:  Sudan J Paediatr       Date:  2022

2.  Subcutaneous Fat Necrosis and Hypercalcemia with Nephrocalcinosis in Infancy: Case Report and Review of the Literature.

Authors:  Katerina Chrysaidou; Georgios Sargiotis; Vasiliki Karava; Dimitrios Liasis; Victor Gourvas; Vissarios Moutsanas; Athanasios Christoforidis; Stella Stabouli
Journal:  Children (Basel)       Date:  2021-05-09

3.  Subcutaneous Fat Necrosis of the Newborn: A Case Report of a Term Infant Presenting with Malaise and Fever at Age of 9 Weeks.

Authors:  Ayuk Adaeze Chikaodinaka; Anikene Chukwuemeka Jude
Journal:  Case Rep Pediatr       Date:  2015-10-08

4.  Subcutaneous fat necrosis of the newborn - An atypical case with typical complications.

Authors:  Cristina Lorenzo; Andreia Romana; Joana Matias; Paulo Calhau
Journal:  Clin Case Rep       Date:  2021-02-18
  4 in total

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