Literature DB >> 26177717

E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation.

Ala-Eddin Al Moustafa1,2,3,4.   

Abstract

It is estimated that 10-20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, the role of onco-viruses in cancer progression to a metastatic form is of particular interest. Recent studies reported that E5 and E6/E7 onco-proteins of high-risk HPVs could enhance cancer progression via the initiation of the epithelial-mesenchymal transition (EMT) event. Herein, we discuss the association between E5 as well as E6/E7 of high-risk HPV and cancer progression.

Entities:  

Keywords:  E5; E6/E7; cancer progression; gene cooperation; high-risk HPV

Mesh：

Substances：

Year:  2015        PMID： 26177717      PMCID： PMC4955364          DOI： 10.1080/19336918.2015.1042197

Source DB:  PubMed          Journal:  Cell Adh Migr        ISSN： 1933-6918            Impact factor:   3.405


  13 in total

1.  A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition.

Authors:  Young-Suk Jung; Ikuko Kato; Hyeong-Reh Choi Kim
Journal:  Biochem Biophys Res Commun       Date:  2013-04-27       Impact factor: 3.575

Review 2.  Human papillomaviruses-related cancers. Presence and prevention strategies in the Middle east and north African regions.

Authors:  Ala-Eddin Al Moustafa; Rana Al-Awadhi; Nabiha Missaoui; Ishag Adam; Raika Durusoy; Lina Ghabreau; Nizar Akil; Hussain Gadelkarim Ahmed; Amber Yasmeen; Ghazi Alsbeih
Journal:  Hum Vaccin Immunother       Date:  2014       Impact factor: 3.452

3.  Human papillomavirus 16 E5 up-regulates the expression of vascular endothelial growth factor through the activation of epidermal growth factor receptor, MEK/ ERK1,2 and PI3K/Akt.

Authors:  S-H Kim; Y-S Juhnn; S Kang; S-W Park; M-W Sung; Y-J Bang; Y-S Song
Journal:  Cell Mol Life Sci       Date:  2006-04       Impact factor: 9.261

4.  E6/E7 of HPV type 16 promotes cell invasion and metastasis of human breast cancer cells.

Authors:  Amber Yasmeen; Tarek A Bismar; Mustapha Kandouz; William D Foulkes; Pierre-Yves Desprez; Ala-Eddin Al Moustafa
Journal:  Cell Cycle       Date:  2007-06-06       Impact factor: 4.534

Review 5.  The biology of human papillomaviruses.

Authors:  Harrison P Nguyen; Marigdalia K Ramírez-Fort; Peter L Rady
Journal:  Curr Probl Dermatol       Date:  2014-03-13

Review 6.  EGF-receptor signaling and epithelial-mesenchymal transition in human carcinomas.

Authors:  Ala-Eddin Al Moustafa; Amal Achkhar; Amber Yasmeen
Journal:  Front Biosci (Schol Ed)       Date:  2012-01-01

7.  Potential impact of a nine-valent vaccine in human papillomavirus related cervical disease.

Authors:  Beatriz Serrano; Laia Alemany; Sara Tous; Laia Bruni; Gary M Clifford; Thomas Weiss; Francesc Xavier Bosch; Silvia de Sanjosé
Journal:  Infect Agent Cancer       Date:  2012-12-29       Impact factor: 2.965

Review 8.  High-Risk HPVs and Human Carcinomas in the Syrian Population.

Authors:  Ala-Eddin Al Moustafa; Lina Ghabreau; Nizar Akil; Samer Rastam; Amal Alachkar; Amber Yasmeen
Journal:  Front Oncol       Date:  2014-04-02       Impact factor: 6.244

9.  NF-κB-induced KIAA1199 promotes survival through EGFR signalling.

Authors:  Kateryna Shostak; Xin Zhang; Pascale Hubert; Serkan Ismail Göktuna; Zheshen Jiang; Iva Klevernic; Julien Hildebrand; Patrick Roncarati; Benoit Hennuy; Aurélie Ladang; Joan Somja; André Gothot; Pierre Close; Philippe Delvenne; Alain Chariot
Journal:  Nat Commun       Date:  2014-11-04       Impact factor: 14.919

Review 10.  Current status of human papillomavirus vaccines.

Authors:  Kwang Sung Kim; Shin Ae Park; Kyung-Nam Ko; Seokjae Yi; Yang Je Cho
Journal:  Clin Exp Vaccine Res       Date:  2014-06-20
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  12 in total

1.  Co-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.

Authors:  Ala-Eddin Al Moustafa; Noor Al-Antary; Tahar Aboulkassim; Nizar Akil; Gerald Batist; Amber Yasmeen
Journal:  Hum Vaccin Immunother       Date:  2016-04-15       Impact factor: 3.452

2.  Co-presence of human papillomaviruses and Epstein-Barr virus is linked with advanced tumor stage: a tissue microarray study in head and neck cancer patients.

Authors:  Hamda Al-Thawadi; Ishita Gupta; Ayesha Jabeen; Faruk Skenderi; Tahar Aboulkassim; Amber Yasmeen; Mohammed I Malki; Gerald Batist; Semir Vranic; Ala-Eddin Al Moustafa
Journal:  Cancer Cell Int       Date:  2020-08-03       Impact factor: 5.722

3.  Co-prevalence of human Papillomaviruses (HPV) and Epstein-Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar.

Authors:  Ishita Gupta; Gheyath K Nasrallah; Anju Sharma; Ayesha Jabeen; Maria K Smatti; Hamda A Al-Thawadi; Ali A Sultan; Moussa Alkhalaf; Semir Vranic; Ala-Eddin Al Moustafa
Journal:  Cancer Cell Int       Date:  2020-04-03       Impact factor: 5.722

4.  The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer.

Authors:  Ishita Gupta; Ayesha Jabeen; Reem Al-Sarraf; Hanan Farghaly; Semir Vranic; Ali A Sultan; Ala-Eddin Al Moustafa; Hamda Al-Thawadi
Journal:  Hum Vaccin Immunother       Date:  2020-10-02       Impact factor: 3.452

5.  Co-presence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples.

Authors:  Mohammed I Malki; Ishita Gupta; Queenie Fernandes; Tahar Aboulkassim; Amber Yasmeen; Semir Vranic; Ala-Eddin Al Moustafa; Hamda A Al-Thawadi
Journal:  Hum Vaccin Immunother       Date:  2020-03-18       Impact factor: 3.452

Review 6.  Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.

Authors:  Queenie Fernandes; Ishita Gupta; Semir Vranic; Ala-Eddin Al Moustafa
Journal:  Pathogens       Date:  2020-04-20

7.  Overexpression of Human Papillomavirus Type 16 Oncoproteins Enhances Epithelial-Mesenchymal Transition via STAT3 Signaling Pathway in Non-Small Cell Lung Cancer Cells.

Authors:  Wenzhang Zhang; Xin Wu; Liang Hu; Yuefan Ma; Zihan Xiu; Bingyu Huang; Yun Feng; Xudong Tang
Journal:  Oncol Res       Date:  2016-12-15       Impact factor: 5.574

8.  Co-prevalence of human Papillomaviruses (HPV) and Epstein-Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar.

Authors:  Ishita Gupta; Gheyath K Nasrallah; Anju Sharma; Ayesha Jabeen; Maria K Smatti; Hamda A Al-Thawadi; Ali A Sultan; Moussa Alkhalaf; Semir Vranic; Ala-Eddin Al Moustafa
Journal:  Cancer Cell Int       Date:  2020-04-03       Impact factor: 5.722

Review 9.  Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.

Authors:  Farhan S Cyprian; Halema F Al-Farsi; Semir Vranic; Saghir Akhtar; Ala-Eddin Al Moustafa
Journal:  Front Oncol       Date:  2018-05-01       Impact factor: 6.244

10.  Human papillomavirus type 18 E5 oncoprotein cooperates with E6 and E7 in promoting cell viability and invasion and in modulating the cellular redox state.

Authors:  Jimena Hochmann; Felipe Parietti; Jennyfer Martínez; Ana C Lopez; Mara Carreño; Celia Quijano; Enrique Boccardo; Laura Sichero; Matías N Möller; Santiago Mirazo; Juan Arbiza
Journal:  Mem Inst Oswaldo Cruz       Date:  2020-03-16       Impact factor: 2.743
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