Literature DB >> 26177230

PyFluor: A Low-Cost, Stable, and Selective Deoxyfluorination Reagent.

Matthew K Nielsen1, Christian R Ugaz1, Wenping Li2, Abigail G Doyle1.   

Abstract

We report an inexpensive, thermally stable deoxyfluorination reagent that fluorinates a broad range of alcohols without substantial formation of elimination side products. This combination of selectivity, safety, and economic viability enables deoxyfluorination on preparatory scale. We employ the [(18)F]-labeled reagent in the first example of a no-carrier-added deoxy-radiofluorination.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26177230     DOI： 10.1021/jacs.5b06307

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  29 in total

1.  Bayesian reaction optimization as a tool for chemical synthesis.

Authors:  Benjamin J Shields; Jason Stevens; Jun Li; Marvin Parasram; Farhan Damani; Jesus I Martinez Alvarado; Jacob M Janey; Ryan P Adams; Abigail G Doyle
Journal:  Nature       Date:  2021-02-03       Impact factor: 49.962

2.  Catalytic One-Step Deoxytrifluoromethylation of Alcohols.

Authors:  Francisco de Azambuja; Sydney M Lovrien; Patrick Ross; Brett R Ambler; Ryan A Altman
Journal:  J Org Chem       Date:  2019-01-25       Impact factor: 4.354

3.  Stereospecific Electrophilic Fluorination of Alkylcarbastannatrane Reagents.

Authors:  Xinghua Ma; Mohamed Diane; Glenn Ralph; Christine Chen; Mark R Biscoe
Journal:  Angew Chem Int Ed Engl       Date:  2017-09-04       Impact factor: 15.336

Review 4.  Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions.

Authors:  Xiaoyun Deng; Jian Rong; Lu Wang; Neil Vasdev; Lei Zhang; Lee Josephson; Steven H Liang
Journal:  Angew Chem Int Ed Engl       Date:  2019-01-14       Impact factor: 15.336

5.  AlkylFluor: Deoxyfluorination of Alcohols.

Authors:  Nathaniel W Goldberg; Xiao Shen; Jiakun Li; Tobias Ritter
Journal:  Org Lett       Date:  2016-11-16       Impact factor: 6.005

Review 6.  Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design.

Authors:  Yunze Wang; Qingyu Lin; Hongcheng Shi; Dengfeng Cheng
Journal:  Front Chem       Date:  2022-06-29       Impact factor: 5.545

Review 7.  Strained Ammonium Precursors for Radiofluorinations.

Authors:  Falco Reissig; Constantin Mamat
Journal:  ChemistryOpen       Date:  2022-06       Impact factor: 2.630

8.  Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions.

Authors:  Ciaran P Seath; David B Vogt; Zihao Xu; Allyson J Boyington; Nathan T Jui
Journal:  J Am Chem Soc       Date:  2018-11-05       Impact factor: 15.419

9.  XtalFluor-E® mediated proto-functionalization of N-vinyl amides: access to N-acetyl N,O-acetals.

Authors:  Y Yi; H Gholami; M G Morrow; B Borhan
Journal:  Org Biomol Chem       Date:  2017-11-22       Impact factor: 3.876

10.  Photoredox-catalyzed aminofluorosulfonylation of unactivated olefins.

Authors:  Tao Zhong; Ji-Tao Yi; Zhi-Da Chen; Quan-Can Zhuang; Yong-Zhao Li; Gui Lu; Jiang Weng
Journal:  Chem Sci       Date:  2021-06-07       Impact factor: 9.825
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.