Fumiyuki Yamasaki1, Takeshi Takayasu2, Ryo Nosaka2, Amatya Jeet Vishwa3, Yukio Takeshima3, Masako Yoshihiro2, Kaoru Kurisu2. 1. Department of Neurosurgery, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan. fyama@hiroshima-u.ac.jp. 2. Department of Neurosurgery, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan. 3. Department of Pathology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, 734-8551, Japan.
Abstract
PURPOSE: We report a very rare case of a fast-growing benign fibrous histiocytoma at the temporal bone. METHODS: A 1-year-old girl was referred for investigation of a right temporal mass that increased during 2-week observation. Imaging studies showed a lytic, loculated skull tumor at the left temporal bone. On magnetic resonance imaging scans, the tumor was isointense on T1- and relatively high-intense on T2-weighted images. The tumor was mostly homogeneously enhanced by gadolinium. On diffusion-weighted images, it was iso- to relatively low-intense; perfusion-weighted images revealed low perfusion. RESULTS: Complete macroscopic resection of the tumor was performed. Immunohistochemical analysis showed that the tumor was positive for CD68 and α-smooth muscle actin and negative for CD1a and CD34; the MIB-1 labeling index was 4 %. A diagnosis of primary benign fibrous histiocytoma of the skull was made. At 6-month follow-up, there were no clinical or radiological signs of tumor recurrence and/or metastasis. CONCLUSIONS: We review the clinical, radiological, and immunohistochemical characteristics of benign fibrous histiocytoma at the skull.
PURPOSE: We report a very rare case of a fast-growing benign fibrous histiocytoma at the temporal bone. METHODS: A 1-year-old girl was referred for investigation of a right temporal mass that increased during 2-week observation. Imaging studies showed a lytic, loculated skull tumor at the left temporal bone. On magnetic resonance imaging scans, the tumor was isointense on T1- and relatively high-intense on T2-weighted images. The tumor was mostly homogeneously enhanced by gadolinium. On diffusion-weighted images, it was iso- to relatively low-intense; perfusion-weighted images revealed low perfusion. RESULTS: Complete macroscopic resection of the tumor was performed. Immunohistochemical analysis showed that the tumor was positive for CD68 and α-smooth muscle actin and negative for CD1a and CD34; the MIB-1 labeling index was 4 %. A diagnosis of primary benign fibrous histiocytoma of the skull was made. At 6-month follow-up, there were no clinical or radiological signs of tumor recurrence and/or metastasis. CONCLUSIONS: We review the clinical, radiological, and immunohistochemical characteristics of benign fibrous histiocytoma at the skull.
Authors: F Bertoni; P Calderoni; P Bacchini; A Sudanese; N Baldini; D Present; M Campanacci Journal: J Bone Joint Surg Am Date: 1986-10 Impact factor: 5.284
Authors: Brigid A Bingham; Daniel A Hatef; Patricia Chevez-Barrios; Shanda H Blackmon; Min P Kim Journal: Clin Nucl Med Date: 2013-03 Impact factor: 7.794