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Literature DB >> 2617440

Protriptyline treatment of sleep hypoxaemia in Duchenne muscular dystrophy.

Abstract

Protriptyline 20 mg daily reduced the total time spent in rapid eye movement sleep in an open study in four subjects with Duchenne muscular dystrophy. Sleep related hypoxaemia and episodes of desaturation were reduced. Anticholinergic side effects were prominent, however, in these patients, precluding its use for regular treatment.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1989 PMID： 2617440 PMCID： PMC1020872 DOI： 10.1136/thx.44.12.1002

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

7 in total

Review 1. A review of the cardiovascular effects and toxicity of tricyclic antidepressants.

Authors: J W Jefferson
Journal: Psychosom Med Date: 1975 Mar-Apr Impact factor: 4.312

2. Effects of protriptyline on sleep related disturbances of breathing in restrictive chest wall disease.

Authors: A K Simonds; R A Parker; M A Branthwaite
Journal: Thorax Date: 1986-08 Impact factor: 9.139

3. Hypoxemia during sleep in Duchenne muscular dystrophy.

Authors: P E Smith; P M Calverley; R H Edwards
Journal: Am Rev Respir Dis Date: 1988-04

4. Sleep apnea: treatment with protriptyline.

Authors: R W Clark; H S Schmidt; S F Schaal; H Boudoulas; D E Schuller
Journal: Neurology Date: 1979-09 Impact factor: 9.910

5. The effects of protriptyline in sleep-disordered breathing.

Authors: P L Smith; E F Haponik; R P Allen; E R Bleecker
Journal: Am Rev Respir Dis Date: 1983-01

6. Protriptyline in the treatment of sleep apnoea.

Authors: W A Conway; F Zorick; P Piccione; T Roth
Journal: Thorax Date: 1982-01 Impact factor: 9.139

7. Differential elevation by protriptyline and depression by diazepam of upper airway respiratory motor activity.

Authors: M Bonora; W M St John; T A Bledsoe
Journal: Am Rev Respir Dis Date: 1985-01

7 in total

4 in total

Protriptyline treatment of sleep hypoxaemia in Duchenne muscular dystrophy.

Review 1. A review of the cardiovascular effects and toxicity of tricyclic antidepressants.

2. Effects of protriptyline on sleep related disturbances of breathing in restrictive chest wall disease.

3. Hypoxemia during sleep in Duchenne muscular dystrophy.

4. Sleep apnea: treatment with protriptyline.

5. The effects of protriptyline in sleep-disordered breathing.

6. Protriptyline in the treatment of sleep apnoea.

7. Differential elevation by protriptyline and depression by diazepam of upper airway respiratory motor activity.

Review 1. Sleep-related breathing disorders. 7. Sleep and breathing problems in general medicine.

Review 2. Sleep Disordered Breathing in Duchenne Muscular Dystrophy.

Review 3. Breathing in Duchenne muscular dystrophy: translation to therapy.

4. Obstructive apnoeas in Duchenne muscular dystrophy.