Literature DB >> 26174081

The impact of the new scene drug "crystal meth" on oral health: a case-control study.

Niklas Rommel1, Nils H Rohleder2, Stefan Wagenpfeil3, Roland Härtel-Petri4, Frederic Jacob2, Klaus-Dietrich Wolff2, Marco R Kesting2.   

Abstract

OBJECTIVE: The use of methamphetamine (MA), a highly addictive stimulant, is rapidly increasing, with MA being widely abused as the scene drug "Crystal Meth" (CM). CM has been associated with severe oral health effects, resulting in so-called "Meth mouth". This term appeared for the first time in 2005 in the literature and describes the final complex of symptoms including rampant caries, periodontal diseases and excessive tooth wear. The aim of this study was to investigate the effects of chronic CM abuse on teeth and intraoral tissue with respect to potential symptoms of Meth mouth.
MATERIALS AND METHODS: In cooperation with two centres for addiction medicine, we performed clinical intraoral investigations in 100 chronic CM users and 100 matched-pair controls. We undertook a caries and periodontal examination by using the clinical parameters DMF-T/DMF-S, bleeding on probing index (BOP) and periodontal screening index (PSI) and tested individual oral hygiene by using approximal space plaque index (API). All clinical data were analysed by the t test for independent samples.
RESULTS: We found significantly larger numbers of caries (p < 0.001) and higher levels of gingival bleeding (p < 0.001) and periodontal disease (p < 0.001) among CM users. Oral hygiene was significantly lower in CM users (p < 0.024).
CONCLUSION: Chronic CM use can lead to extensive potential damage within the intraoral cavity. When CM is used over a long period of time and in the absence of treatment, clinical symptoms in terms of Meth mouth syndrome cannot be excluded. CLINICAL RELEVANCE: Based on our results, we recommend a specific prevention and therapeutic concept including educational campaigns for MA users and specialized dental care for CM patients.

Entities:  

Keywords:  Caries; Crystal methamphetamine; Meth mouth; Oral hygiene; Periodontal diseases; Prevalence study

Mesh:

Substances:

Year:  2015        PMID: 26174081     DOI: 10.1007/s00784-015-1527-z

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  39 in total

1.  "Meth mouth".

Authors:  Anne-Marie L Laslett; John N Crofts
Journal:  Med J Aust       Date:  2007-06-18       Impact factor: 7.738

2.  Oral health of representative samples of Germans examined in 1989 and 1992.

Authors:  W Micheelis; J Bauch
Journal:  Community Dent Oral Epidemiol       Date:  1996-02       Impact factor: 3.383

3.  Usefulness of saliva for measurement of 3,4-methylenedioxymethamphetamine and its metabolites: correlation with plasma drug concentrations and effect of salivary pH.

Authors:  M Navarro; S Pichini; M Farré; J Ortuño; P N Roset; J Segura; R de la Torre
Journal:  Clin Chem       Date:  2001-10       Impact factor: 8.327

Review 4.  Comprehensive dental treatment for "meth mouth": a case report and literature review.

Authors:  Panpan Wang; Xinmei Chen; Liwei Zheng; Lan Guo; Xin Li; Simin Shen
Journal:  J Formos Med Assoc       Date:  2012-06-09       Impact factor: 3.282

5.  The relationship between methamphetamine use and increased dental disease.

Authors:  Vivek Shetty; Larissa J Mooney; Corwin M Zigler; Thomas R Belin; Debra Murphy; Richard Rawson
Journal:  J Am Dent Assoc       Date:  2010-03       Impact factor: 3.634

6.  Methamphetamine abuse and "meth mouth".

Authors:  Nelson L Rhodus; James W Little
Journal:  Northwest Dent       Date:  2005 Sep-Oct

7.  Methamphetamine cytotoxicity and effect on LPS-stimulated IL-1beta production by human monocytes.

Authors:  D A Tipton; Z T Legan; M Kh Dabbous
Journal:  Toxicol In Vitro       Date:  2009-11-27       Impact factor: 3.500

8.  Cocaine and oral health.

Authors:  H S Brand; S Gonggrijp; C J Blanksma
Journal:  Br Dent J       Date:  2008-04-12       Impact factor: 1.626

Review 9.  Methamphetamine abuse and dentistry: a review of the literature and presentation of a clinical case.

Authors:  Jason H Goodchild; Mark Donaldson
Journal:  Quintessence Int       Date:  2007 Jul-Aug       Impact factor: 1.677

Review 10.  Saliva and dental erosion.

Authors:  Marília Afonso Rabelo Buzalaf; Angélicas Reis Hannas; Melissa Thiemi Kato
Journal:  J Appl Oral Sci       Date:  2012 Sep-Oct       Impact factor: 2.698

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  7 in total

1.  Methamphetamine Users Have Increased Dental Disease: A Propensity Score Analysis.

Authors:  V Shetty; L Harrell; J Clague; D A Murphy; B A Dye; T R Belin
Journal:  J Dent Res       Date:  2016-03-18       Impact factor: 6.116

2.  Periodontal status of current methamphetamine users.

Authors:  Vladimir W Spolsky; Jason Clague; Debra A Murphy; Steven Vitero; Bruce A Dye; Thomas R Belin; Vivek Shetty
Journal:  J Am Dent Assoc       Date:  2018-03       Impact factor: 3.634

3.  The effect of methamphetamine abuse on dental caries and periodontal diseases in an Eastern China city.

Authors:  Tao Ye; Dongliang Sun; Guangying Dong; Guangjie Xu; Ligang Wang; Jinjin Du; Pengcheng Ren; Shibin Yu
Journal:  BMC Oral Health       Date:  2018-01-10       Impact factor: 2.757

4.  Meth Mouth-A Growing Epidemic in Dentistry?

Authors:  Andreas Pabst; Juan Carlos Castillo-Duque; Axel Mayer; Marcus Klinghuber; Richard Werkmeister
Journal:  Dent J (Basel)       Date:  2017-10-30

5.  Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis.

Authors:  Mohsen Yazdanian; Bahram Armoon; Alireza Noroozi; Rasool Mohammadi; Amir-Hosein Bayat; Elahe Ahounbar; Peter Higgs; Hormoz Sanaei Nasab; Azadeh Bayani; Morteza Hemmat
Journal:  BMC Oral Health       Date:  2020-02-10       Impact factor: 2.757

6.  Methamphetamine use and oral health-related quality of life.

Authors:  Amrita Mukherjee; Bruce A Dye; Jason Clague; Thomas R Belin; Vivek Shetty
Journal:  Qual Life Res       Date:  2018-08-03       Impact factor: 3.440

Review 7.  [Differential diagnostic distinction between substance-induced and primary psychoses: : Recommendations for general psychiatric and forensic practice].

Authors:  Dusan Hirjak; Andreas Meyer-Lindenberg; Geva A Brandt; Harald Dreßing
Journal:  Nervenarzt       Date:  2021-03-03       Impact factor: 1.214

  7 in total

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