Literature DB >> 26173109

Correction: IDO1 and IDO2 Non-Synonymous Gene Variants: Correlation with Crohn's Disease Risk and Clinical Phenotype.

Alexander Lee, Navya Kanuri, Yuanhao Zhang, Gregory S Sayuk, Ellen Li, Matthew A Ciorba.   

Abstract

Entities:  

Year:  2015        PMID: 26173109      PMCID: PMC4501741          DOI: 10.1371/journal.pone.0133098

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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Table 2 is incorrect. Please see the corrected Table 2 here.
Table 2

Expected and identified frequency of patients with IDO2 Variant Alleles.

Recessive Logistic ModelNumber (and %) of minor alleles
Predicted Minor allele frequencyEstimate coefficientP-valueRaceNon-IBD (N = 177)CD (N = 686)
rs4503083 (T to A) 10.9%–50.0% -1.295 0.025 White het: 58 (40.8%) het: 196 (31.9%)
Y359stop homo: 8 (5.6%) homo: 19 (3.1%)
total: 142 total: 614
Black het: 5 (14.7%) het: 12 (19%)
homo: 1 (2.9%) homo: 1 (1.6%)
total: 34 total: 63
Other het: 0 (0%) het: 7 (77.8%)
homo: 0 (0%) homo: 0 (0%)
total: 1 total: 9
rs4736794 (A to G)6.7%–50.0%-0.4980.698Whitehet: 27 (19%)het: 92 (15%)
homo: 2 (1.4%)homo: 4 (0.7%)
total: 142total: 614
Blackhet: 2 (5.9%)het: 2 (3.2%)
homo: 0 (0%)homo: 0 (0%)
total: 34total:63
Otherhet: 0 (0%)het: 6 (66.7%)
homo: 0 (0%)homo: 0(0%)
total: 1total: 9
rs10109853 (C to T)18.2%–100%-0.0720.786Whitehet: 65 (45.8%)het: 316 (51.5%)
homo: 32 (22.5%)homo: 157 (25.6%)
total: 142total: 614
Blackhet: 13 (38.2%)het: 26 (41.3%)
homo: 7 (20.6%)homo: 9 (14.3%)
total: 34total: 63
Otherhet: 0 (0%)het: 6 (66.7%)
homo: 1 (100%)homo: 1 (11.1%)
total: 1total: 9
rs35212142(T to A)5.6%–50.0%12.9230.981Whitehet: 8 (5.6%)het: 26 (4.2%)
homo: 0 (0%)homo: 2 (0.3%)
total: 142total: 614
Blackhet: 2 (5.9%)het: 0 (0%)
homo: 0 (0%)homo: 0 (0%)
total: 34total: 63
Otherhet: 0 (0%)het: 0 (0%)
homo: 0 (0%)homo: 0 (0%)
total: 1total: 9
  1 in total

1.  IDO1 and IDO2 non-synonymous gene variants: correlation with crohn's disease risk and clinical phenotype.

Authors:  Alexander Lee; Navya Kanuri; Yuanhao Zhang; Gregory S Sayuk; Ellen Li; Matthew A Ciorba
Journal:  PLoS One       Date:  2014-12-26       Impact factor: 3.240

  1 in total

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