Rohini Handa1, U R K Rao2, Juliana F M Lewis3, Gautam Rambhad4, Susan Shiff5, Canna J Ghia4. 1. Indraprastha Apollo Hospital, New Delhi, India. 2. Sri Deepti Rheumatology Centre, Hyderabad, India. 3. Evidera, Meta Research, Lexington, MA, USA. 4. Pfizer Inc., Mumbai, India. 5. Pfizer Inc., New York, NY, USA.
Abstract
AIM: Rheumatoid arthritis (RA) can lead to severe disability. This literature review assessed the descriptive epidemiology, comorbidities and extra-articular manifestations, functioning abilities and quality of life, and treatment patterns of RA patients in India. METHOD: A literature review of all observational studies published from 1985 to 2012 was conducted using MEDLINE and Embase. Quantitative and qualitative findings were summarized. RESULTS: Twenty-eight studies were identified for data extraction. Seven described the descriptive epidemiology of RA, 14 described comorbidities and extra-articular manifestations, nine described the functioning abilities and quality of life among patients, and 10 provided information on treatments. CONCLUSION: This review is confined to studies with small sample sizes, cross-sectional designs, and/or clinical settings that may not be representative of the entire Indian population. There is a need for more robust studies, as conclusions for the entire Indian RA population cannot be drawn from only the current observational studies.
AIM: Rheumatoid arthritis (RA) can lead to severe disability. This literature review assessed the descriptive epidemiology, comorbidities and extra-articular manifestations, functioning abilities and quality of life, and treatment patterns of RApatients in India. METHOD: A literature review of all observational studies published from 1985 to 2012 was conducted using MEDLINE and Embase. Quantitative and qualitative findings were summarized. RESULTS: Twenty-eight studies were identified for data extraction. Seven described the descriptive epidemiology of RA, 14 described comorbidities and extra-articular manifestations, nine described the functioning abilities and quality of life among patients, and 10 provided information on treatments. CONCLUSION: This review is confined to studies with small sample sizes, cross-sectional designs, and/or clinical settings that may not be representative of the entire Indian population. There is a need for more robust studies, as conclusions for the entire Indian RA population cannot be drawn from only the current observational studies.
Authors: Diego Prieto; Camila González; Laura Weber; Ornella Realini; Karina Pino-Lagos; Maria José Bendek; Ignacio Retamal; Víctor Beltrán; Juan Pablo Riedemann; Francisco Espinoza; Alejandra Chaparro Journal: J Oral Biol Craniofac Res Date: 2021-02-22