Literature DB >> 26171067

Lung cancer with spontaneous regression of primary and metastatic sites: A case report.

Ryoko Ogawa1, Hiroko Watanabe1, Kai Yazaki1, Kazutaka Fujita1, Yoshiya Tsunoda1, Kensuke Nakazawa1, Shinsuke Homma1, Katsunori Kagohashi2, Hiroaki Satoh2, Nobuyuki Hizawa1.   

Abstract

Partial or complete spontaneous cancer regression is a rare phenomenon, particularly in patients with lung cancer. This is the case report of a patient with lung cancer who exhibited spontaneous regression of the primary as well as metastatic lesions, without receiving any treatment. Spontaneous regression commenced within a week of obtaining pathological specimens by transbronchial and percutaneous biopsies from the primary lesion and metastatic lymph nodes of the left side of the neck. The reason for this phenomenon is unknown; however, we hypothesized that there may be an immunological association between the stimulus of the biopsies and the spontaneous regression. This patient should be closely followed up to monitor the clinical course of this unusual case.

Entities:  

Keywords:  lung cancer; metastasis; primary tumor; spontaneous regression

Year:  2015        PMID: 26171067      PMCID: PMC4487128          DOI: 10.3892/ol.2015.3243

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  17 in total

1.  Spontaneous regression of pulmonary metastases demonstrated by CT.

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Journal:  Br J Radiol       Date:  1999-03       Impact factor: 3.039

2.  Autologous killing by a population of intermediate T-cell receptor cells and its NK1.1+ and NK1.1- subsets, using Fas ligand/Fas molecules.

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3.  Protective effect of NK1.1(+) T cells as well as NK cells against intraperitoneal tumors in mice.

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Journal:  Cell Immunol       Date:  1999-05-01       Impact factor: 4.868

Review 4.  The spontaneous regression of cancer. A review of cases from 1900 to 1987.

Authors:  G B Challis; H J Stam
Journal:  Acta Oncol       Date:  1990       Impact factor: 4.089

5.  Spontaneous regression of pulmonary metastasis from nonfunctioning adrenocortical carcinoma after removal of the primary lesion: a case report.

Authors:  K Gohji; T Kizaki; A Fujii
Journal:  J Urol       Date:  1995-11       Impact factor: 7.450

Review 6.  Complete spontaneous remission in a patient with metastatic non-small-cell lung cancer. Case report, review of the literature, and discussion of possible biological pathways involved.

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Journal:  Ann Oncol       Date:  1997-10       Impact factor: 32.976

7.  Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy.

Authors:  S G Marcus; P L Choyke; R Reiter; G S Jaffe; R B Alexander; W M Linehan; S A Rosenberg; M M Walther
Journal:  J Urol       Date:  1993-08       Impact factor: 7.450

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Authors:  W H Cole
Journal:  J Surg Oncol       Date:  1981       Impact factor: 3.454

9.  Spontaneous regression of choroidal metastasis from renal cell carcinoma.

Authors:  Amjad M Hammad; Gianmarco R Paris; Wichard A J van Heuven; Ian M Thompson; Thomas D Fitzsimmons
Journal:  Am J Ophthalmol       Date:  2003-06       Impact factor: 5.258

10.  Specific organ metastases and survival in small cell lung cancer.

Authors:  Kensuke Nakazawa; Koichi Kurishima; Tomohiro Tamura; Katsunori Kagohashi; Hiroichi Ishikawa; Hiroaki Satoh; Nobuyuki Hizawa
Journal:  Oncol Lett       Date:  2012-07-09       Impact factor: 2.967

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  7 in total

1.  Spontaneous regression of lung squamous cell carcinoma with synchronous mediastinal progression: A case report.

Authors:  Takuya Matsui; Tetsuya Mizuno; Hiroaki Kuroda; Noriaki Sakakura; Takaaki Arimura; Yasushi Yatabe; Yukinori Sakao
Journal:  Thorac Cancer       Date:  2018-10-11       Impact factor: 3.500

2.  Spontaneous Regression of Non-small Cell Lung Cancer: A Case Report and Literature Review.

Authors:  Ashley Shatola; Ky Nam Nguyen; Elham Kamangar; Megan E Daly
Journal:  Cureus       Date:  2020-01-12

3.  Pulmonary artery coil embolisation prevented tumour progression in a patient with advanced squamous cell lung carcinoma.

Authors:  Virginija Šileikienė; Viktorija Gurskytė; Ingrida Zeleckienė; Elena Bernotienė; Sigitas Čibiras
Journal:  Ups J Med Sci       Date:  2020-04-30       Impact factor: 2.384

Review 4.  Spontaneous regression of ALK fusion protein-positive non-small cell lung carcinoma: a case report and review of the literature.

Authors:  Maria Walls; Gerard M Walls; Jacqueline A James; Kyle T Crawford; Hossam Abdulkhalek; Tom B Lynch; Aaron J Peace; Terry E McManus; O Rhun Evans
Journal:  BMC Pulm Med       Date:  2020-08-06       Impact factor: 3.317

5.  Spontaneous regression of locally advanced nonsmall cell lung cancer: A case report.

Authors:  Kiat Huat Ooi; Timothy Cheo; Gwyneth Shook Ting Soon; Cheng Nang Leong
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.817

Review 6.  Spontaneous remission of advanced progressive poorly differentiated non-small cell lung cancer: a case report and review of literature.

Authors:  Hee-Young Yoon; Heae Surng Park; Min Sun Cho; Sung Shin Shim; Yookyung Kim; Jin Hwa Lee
Journal:  BMC Pulm Med       Date:  2019-11-11       Impact factor: 3.317

7.  Regression of Lung Squamous Cell Carcinoma after the Withdrawal of Cyclosporin A Combined with Pirfenidone Treatment in a Patient with Idiopathic Pulmonary Fibrosis.

Authors:  Mari Takahashi; Yukihiro Horio; Takahisa Takihara; Keito Enokida; Masashi Miyaoka; Kenichi Hirabayashi; Kana Ohshinden; Shigeaki Hattori; Fuminari Takahashi; Genki Takahashi; Jun Tanaka; Hiroto Takiguchi; Kyoko Niimi; Yoko Ito; Naoki Hayama; Tsuyoshi Oguma; Koichiro Asano
Journal:  Intern Med       Date:  2020-10-07       Impact factor: 1.271

  7 in total

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