Jacob Lahr1, Christina Schwartz, Bernhard Heimbach, Ad Aertsen, Jörn Rickert, Tonio Ball. 1. Freiburg Brain Imaging, University Medical Center, Freiburg, Germany. Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany. Department of Neurology, University Medical Center, Freiburg, Germany. Intracranial EEG and Brain Imaging Group, University Medical Center, Freiburg, Germany.
Abstract
OBJECTIVE: Brain-machine interfaces (BMI) are an emerging therapeutic option that can allow paralyzed patients to gain control over assistive technology devices (ATDs). BMI approaches can be broadly classified into invasive (based on intracranially implanted electrodes) and noninvasive (based on skin electrodes or extracorporeal sensors). Invasive BMIs have a favorable signal-to-noise ratio, and thus allow for the extraction of more information than noninvasive BMIs, but they are also associated with the risks related to neurosurgical device implantation. Current noninvasive BMI approaches are typically concerned, among other issues, with long setup times and/or intensive training. Recent studies have investigated the attitudes of paralyzed patients eligible for BMIs, particularly patients affected by amyotrophic lateral sclerosis (ALS). These studies indicate that paralyzed patients are indeed interested in BMIs. Little is known, however, about the degree of knowledge among paralyzed patients concerning BMI approaches or about how patients retrieve information on ATDs. Furthermore, it is not yet clear if paralyzed patients would accept intracranial implantation of BMI electrodes with the premise of decoding improvements, and what the attitudes of a broader range of patients with diseases such as stroke or spinal cord injury are towards this new kind of treatment. APPROACH: Using a questionnaire, we surveyed 131 paralyzed patients for their opinions on invasive BMIs and their attitude toward invasive BMI treatment options. MAIN RESULTS: The majority of the patients knew about and had a positive attitude toward invasive BMI approaches. The group of ALS patients was especially open to the concept of BMIs. The acceptance of invasive BMI technology depended on the improvements expected from the technology. Furthermore, the survey revealed that for paralyzed patients, the Internet is an important source of information on ATDs. SIGNIFICANCE: Websites tailored to prospective BMI users should be further developed to provide reliable information to patients, and also to help to link prospective BMI users with researchers involved in the development of BMI technology.
OBJECTIVE: Brain-machine interfaces (BMI) are an emerging therapeutic option that can allow paralyzedpatients to gain control over assistive technology devices (ATDs). BMI approaches can be broadly classified into invasive (based on intracranially implanted electrodes) and noninvasive (based on skin electrodes or extracorporeal sensors). Invasive BMIs have a favorable signal-to-noise ratio, and thus allow for the extraction of more information than noninvasive BMIs, but they are also associated with the risks related to neurosurgical device implantation. Current noninvasive BMI approaches are typically concerned, among other issues, with long setup times and/or intensive training. Recent studies have investigated the attitudes of paralyzedpatients eligible for BMIs, particularly patients affected by amyotrophic lateral sclerosis (ALS). These studies indicate that paralyzedpatients are indeed interested in BMIs. Little is known, however, about the degree of knowledge among paralyzedpatients concerning BMI approaches or about how patients retrieve information on ATDs. Furthermore, it is not yet clear if paralyzedpatients would accept intracranial implantation of BMI electrodes with the premise of decoding improvements, and what the attitudes of a broader range of patients with diseases such as stroke or spinal cord injury are towards this new kind of treatment. APPROACH: Using a questionnaire, we surveyed 131 paralyzedpatients for their opinions on invasive BMIs and their attitude toward invasive BMI treatment options. MAIN RESULTS: The majority of the patients knew about and had a positive attitude toward invasive BMI approaches. The group of ALSpatients was especially open to the concept of BMIs. The acceptance of invasive BMI technology depended on the improvements expected from the technology. Furthermore, the survey revealed that for paralyzedpatients, the Internet is an important source of information on ATDs. SIGNIFICANCE: Websites tailored to prospective BMI users should be further developed to provide reliable information to patients, and also to help to link prospective BMI users with researchers involved in the development of BMI technology.
Authors: Mariana P Branco; Elmar G M Pels; Femke Nijboer; Nick F Ramsey; Mariska J Vansteensel Journal: Disabil Rehabil Assist Technol Date: 2021-08-12
Authors: Maxime Verwoert; Mariska J Vansteensel; Zachary V Freudenburg; Erik J Aarnoutse; Frans S S Leijten; Nick F Ramsey; Mariana P Branco Journal: J Neural Eng Date: 2021-10-22 Impact factor: 5.043
Authors: Sergei L Shishkin; Yuri O Nuzhdin; Evgeny P Svirin; Alexander G Trofimov; Anastasia A Fedorova; Bogdan L Kozyrskiy; Boris M Velichkovsky Journal: Front Neurosci Date: 2016-11-18 Impact factor: 4.677
Authors: Sam E John; Nicholas L Opie; Yan T Wong; Gil S Rind; Stephen M Ronayne; Giulia Gerboni; Sebastien H Bauquier; Terence J O'Brien; Clive N May; David B Grayden; Thomas J Oxley Journal: Sci Rep Date: 2018-05-30 Impact factor: 4.379
Authors: Mariana P Branco; Elmar G M Pels; Ruben H Sars; Erik J Aarnoutse; Nick F Ramsey; Mariska J Vansteensel; Femke Nijboer Journal: Neurorehabil Neural Repair Date: 2021-02-03 Impact factor: 3.919