Peter H Connolly1, Andrew J Meltzer2, Jason A Spector3, Darren B Schneider2. 1. Division of Vascular and Endovascular Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY. Electronic address: pec9018@med.cornell.edu. 2. Division of Vascular and Endovascular Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY. 3. Division of Plastic and Reconstructive Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY.
Abstract
BACKGROUND: In cases of severe vascular trauma, traditional means for assessing viability using Doppler and angiography can have limited application. Indocyanine green angiography (ICGA) allows for a rapid qualitative assessment of tissue perfusion that serves as an important adjunct to these traditional methods, which can also be particularly helpful in guiding therapy. METHODS/ RESULTS: We present a case of complicated ankle fracture with severe vascular compromise, which illustrates the role of ICGA as an assessment tool to guide therapy and decision-making in cases of acute limb threat. ICGA using SPY system (Novadaq, Bonita Springs, FL) was performed as part of our initial assessment to evaluate the extent of malperfusion and potential for revascularization. Preprocedural imaging with ICGA showed very limited uptake in the foot. Treatment was also performed with traditional angiography and infusion of intra-arterial nitroglycerin into the posterior tibial artery. Postprocedure imaging with ICGA was performed a day later and showed marked difference in the perfusion profile, with rapid uptake into the forefoot and toes, which corresponded with the patient's clinical improvement. The patient went on to have complete limb salvage. CONCLUSIONS: The addition of ICGA for assessment of tissue perfusion in cases of complex vascular trauma has several implications: it guides surgical therapy for excision of devitalized tissue and aids in decision-making for major considerations such as revascularization efforts or amputation.
BACKGROUND: In cases of severe vascular trauma, traditional means for assessing viability using Doppler and angiography can have limited application. Indocyanine green angiography (ICGA) allows for a rapid qualitative assessment of tissue perfusion that serves as an important adjunct to these traditional methods, which can also be particularly helpful in guiding therapy. METHODS/ RESULTS: We present a case of complicated ankle fracture with severe vascular compromise, which illustrates the role of ICGA as an assessment tool to guide therapy and decision-making in cases of acute limb threat. ICGA using SPY system (Novadaq, Bonita Springs, FL) was performed as part of our initial assessment to evaluate the extent of malperfusion and potential for revascularization. Preprocedural imaging with ICGA showed very limited uptake in the foot. Treatment was also performed with traditional angiography and infusion of intra-arterial nitroglycerin into the posterior tibial artery. Postprocedure imaging with ICGA was performed a day later and showed marked difference in the perfusion profile, with rapid uptake into the forefoot and toes, which corresponded with the patient's clinical improvement. The patient went on to have complete limb salvage. CONCLUSIONS: The addition of ICGA for assessment of tissue perfusion in cases of complex vascular trauma has several implications: it guides surgical therapy for excision of devitalized tissue and aids in decision-making for major considerations such as revascularization efforts or amputation.
Authors: Jonathan T Elliott; Rocco R Addante; Gerard-Paul Slobegean; Shudong Jiang; Eric R Henderson; Brian W Pogue; Ida Leah Gitajn Journal: J Biomed Opt Date: 2020-06 Impact factor: 3.170