A prospective study of urinary tract infection during pelvic radiotherapy.

The frequency of urinary tract infection before and during pelvic radiotherapy was studied prospectively in 172 patients who were not catheterised and had not had instrumentation for at least 4 weeks prior to radiotherapy. The incidence of urinary tract infection prior to radiotherapy was 17% and a further 17% of patients developed a urinary tract infection during radiotherapy. Mid-stream specimens of urine (MSU) should be examined for infection on a weekly basis during pelvic radiotherapy not only to identify this additional 17% of patients but also to detect those patients who have persistent urinary tract infection in spite of treatment with appropriate antibiotics.