Shahida Shahrir1, Hilary A Tindle2, Kathleen A McGinnis3, David A Fiellin4, Joseph Goulet3,4, Kathleen M Akgün3,4, Cynthia L Gibert5, Maria C Rodriguez-Barradas6, Kristina Crothers1. 1. a Harborview Medical Center, University of Washington , Seattle , Washington , USA. 2. b University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania , USA. 3. c VA Connecticut HealthCare System , West Haven , Connecticut , USA. 4. d Yale University School of Medicine , New Haven , Connecticut , USA. 5. e Washington DC VA Medical Center , Washington , DC , USA. 6. f Michael DeBakey VA Medical Center , Houston , Texas , USA.
Abstract
BACKGROUND: As antiretroviral treatments prolong life in human immunodeficiency virus (HIV)-infected patients, smoking cessation is now a top priority. However, studies of HIV-infected smokers have not been conducted with uninfected controls. In this study, researchers determined factors associated with contemplating smoking cessation and making a prior quit attempt among HIV-infected and uninfected smoking veterans. METHODS: Between 2005 and 2007, 1,027 HIV-infected and 794 uninfected smokers were identified as part of the Veterans Aging Cohort Study (VACS). Stratifying by HIV status, adjusted odds ratios (AORs) were calculated using logistic regression to identify factors associated with contemplating smoking cessation and making a prior quit attempt. RESULTS: Most participants (66 % of HIV-infected vs. 68 % of uninfected; P = .46) were contemplating cessation, and 56 % of both groups (P = .99) had attempted to quit in the last year. In stratified multivariable analyses, HIV-infected smokers with recent pulmonary disease diagnoses were more likely to have made a quit attempt (AOR = 4.93, 95 % confidence interval [CI] = 1.41-17.17). Both HIV-infected and uninfected patients with unhealthy alcohol use were less likely to be contemplating cessation (AOR = 0.66, 95 % CI = 0.49-0.90 and 0.71, 95 % CI = 0.50-1.00). HIV-infected smokers who reported unhealthy alcohol use were also less likely to have made a quit attempt in the last year (AOR = 0.68, 95 % CI = 0.51-0.91). CONCLUSIONS: Patient-level interest and motivation are not major barriers to smoking cessation among HIV-infected veterans. Targeting HIV-infected smokers with a recent pulmonary disease diagnosis may improve sustained smoking cessation. Unhealthy alcohol use appears to be a key modifiable risk factor. Smoking cessation rates may be improved by combining interventions for smoking and alcohol use for HIV-infected patients.
BACKGROUND: As antiretroviral treatments prolong life in human immunodeficiency virus (HIV)-infectedpatients, smoking cessation is now a top priority. However, studies of HIV-infected smokers have not been conducted with uninfected controls. In this study, researchers determined factors associated with contemplating smoking cessation and making a prior quit attempt among HIV-infected and uninfected smoking veterans. METHODS: Between 2005 and 2007, 1,027 HIV-infected and 794 uninfected smokers were identified as part of the Veterans Aging Cohort Study (VACS). Stratifying by HIV status, adjusted odds ratios (AORs) were calculated using logistic regression to identify factors associated with contemplating smoking cessation and making a prior quit attempt. RESULTS: Most participants (66 % of HIV-infected vs. 68 % of uninfected; P = .46) were contemplating cessation, and 56 % of both groups (P = .99) had attempted to quit in the last year. In stratified multivariable analyses, HIV-infected smokers with recent pulmonary disease diagnoses were more likely to have made a quit attempt (AOR = 4.93, 95 % confidence interval [CI] = 1.41-17.17). Both HIV-infected and uninfected patients with unhealthy alcohol use were less likely to be contemplating cessation (AOR = 0.66, 95 % CI = 0.49-0.90 and 0.71, 95 % CI = 0.50-1.00). HIV-infected smokers who reported unhealthy alcohol use were also less likely to have made a quit attempt in the last year (AOR = 0.68, 95 % CI = 0.51-0.91). CONCLUSIONS:Patient-level interest and motivation are not major barriers to smoking cessation among HIV-infected veterans. Targeting HIV-infected smokers with a recent pulmonary disease diagnosis may improve sustained smoking cessation. Unhealthy alcohol use appears to be a key modifiable risk factor. Smoking cessation rates may be improved by combining interventions for smoking and alcohol use for HIV-infectedpatients.
Authors: Krishna P Reddy; Robert A Parker; Elena Losina; Travis P Baggett; A David Paltiel; Nancy A Rigotti; Milton C Weinstein; Kenneth A Freedberg; Rochelle P Walensky Journal: J Infect Dis Date: 2016-11-03 Impact factor: 5.226
Authors: Virginia A Triant; Ellie Grossman; Nancy A Rigotti; Rekha Ramachandran; Susan Regan; Scott E Sherman; Kimber P Richter; Hilary A Tindle; Kathleen F Harrington Journal: Nicotine Tob Res Date: 2020-06-12 Impact factor: 4.244
Authors: Shahida Shahrir; Kristina Crothers; Kathleen A McGinnis; Kwun C G Chan; Jared M Baeten; Sarah M Wilson; Adeel A Butt; Margaret A Pisani; Stephen R Baldassarri; Amy Justice; Emily C Williams Journal: Prog Cardiovasc Dis Date: 2020-01-24 Impact factor: 8.194
Authors: Krishna P Reddy; Chung Yin Kong; Emily P Hyle; Travis P Baggett; Mingshu Huang; Robert A Parker; A David Paltiel; Elena Losina; Milton C Weinstein; Kenneth A Freedberg; Rochelle P Walensky Journal: JAMA Intern Med Date: 2017-11-01 Impact factor: 44.409