Literature DB >> 26167349

Successful Treatment of Refractory Gastrointestinal Bleeding by Systemic (Oral) Ankaferd Blood Stopper in a Patient with Glanzmann Thrombasthenia.

Sibel Kabukçu Hacıoğlu1, Mehmet Hilmi Doğu1, İsmail Sarı1, Ali Keskin1.   

Abstract

BACKGROUND: Glanzmann Thrombasthenia (GT) is a genetic platelet dysfunction and a life threatening disease. Ankaferd Blood Stopper (ABS) is a topical hemostatic agent of herbal origin which has been recently made available for clinical use. Its hemostatic effect is independent from blood clotting factors and occurs as a result of the aggregation of focal red blood cells by an encapsulated protein web. CASE REPORT: In this paper, a patient with GT is presented in whom 3 months of gastrointestinal bleeding refractory to all medical therapies was controlled within a short time of using oral ABS.
CONCLUSION: The difference between this patient and other cases presented in the medical literature is the oral use of ABS. Thus, this patient may contribute to the medical community in showing the safety and efficacy of systemic (oral) ABS in patients with disorders of coagulation. However, there is a need for more patient experiences.

Entities:  

Keywords:  Ankaferd Blood Stopper; Glanzmann thrombasthenia; disorders of hemostasis; oral systemic administration

Year:  2015        PMID: 26167349      PMCID: PMC4432705          DOI: 10.5152/balkanmedj.2015.15734

Source DB:  PubMed          Journal:  Balkan Med J        ISSN: 2146-3123            Impact factor:   2.021


  14 in total

1.  Controlling of upper gastrointestinal bleeding associated with severe immune thrombocytopenia via topical adjunctive application of Ankaferd blood stopper.

Authors:  Burak Ozseker; Ali Shorbagi; Cumali Efe; Ibrahim C Haznedaroglu; Yusuf Bayraktar
Journal:  Blood Coagul Fibrinolysis       Date:  2012-07       Impact factor: 1.276

Review 2.  Evaluation of hemostatic effects of Ankaferd as an alternative medicine.

Authors:  Yavuz Beyazit; Mevlut Kurt; Murat Kekilli; Hakan Goker; Ibrahim Celalettin Haznedaroglu
Journal:  Altern Med Rev       Date:  2010-12

3.  Management of persistent gastric bleeding in a patient with Glanzmann's thrombasthenia.

Authors:  Suzanne Bakdash; John M Lyons; Sheldon I Bastacky; Michael A Pezzone; James B McGee; Robert E Schoen; Miguel Regueiro; Kenneth K Lee; Franklin A Bontempo
Journal:  Am J Hematol       Date:  2008-05       Impact factor: 10.047

4.  Ankaferd hemostat in the management of gastrointestinal hemorrhages.

Authors:  Yavuz Beyazit; Murat Kekilli; Ibrahim C Haznedaroglu; Ertugrul Kayacetin; Metin Basaranoglu
Journal:  World J Gastroenterol       Date:  2011-09-21       Impact factor: 5.742

5.  Recombinant activated factor VII usage in life threatening hemorrhage: a pediatric experience.

Authors:  Sunil Bhat; Satya Prakash Yadav; Madasu Anjan; Veronique Dinand; Anupam Sachdeva
Journal:  Indian J Pediatr       Date:  2011-02-17       Impact factor: 1.967

6.  Tandem oral, rectal, and nasal administrations of Ankaferd Blood Stopper to control profuse bleeding leading to hemodynamic instability.

Authors:  Mevlut Kurt; Erkin Oztas; Sedef Kuran; Ibrahim K Onal; Murat Kekilli; Ibrahim C Haznedaroglu
Journal:  Am J Emerg Med       Date:  2009-06       Impact factor: 2.469

7.  Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience.

Authors:  Timucin Baykul; E Guchan Alanoglu; Gulperi Kocer
Journal:  J Contemp Dent Pract       Date:  2010-01-01

Review 8.  Glanzmann thrombasthenia: an update.

Authors:  Massimo Franchini; Emmanuel J Favaloro; Giuseppe Lippi
Journal:  Clin Chim Acta       Date:  2009-10-23       Impact factor: 3.786

9.  Topical Ankaferd hemostat application for the management of oral cavity bleedings in children with hemorrhagic diathesis.

Authors:  Goksel Leblebisatan; Ali Bay; Suleyman C Karakus; Murat Kekilli; Ibrahim C Haznedaroglu
Journal:  Blood Coagul Fibrinolysis       Date:  2012-09       Impact factor: 1.276

10.  Oral high-dose ankaferd administration effects on gastrointestinal system.

Authors:  Erdem Akbal; Seyfettin Köklü; Hesna Müzeyyen Astarcı; Erdem Koçak; Gökhan Karaca; Yavuz Beyazıt; Güler Topcu; Bilgehan Acar; Dilek Ergün; İbrahim Celalettin Haznedaroğlu
Journal:  Int J Med Sci       Date:  2013-03-02       Impact factor: 3.738

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