Literature DB >> 26167340

New Predictive Parameters of Bell's Palsy: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio.

Doğan Atan1, Aykut İkincioğulları1, Sabri Köseoğlu2, Kürşat Murat Özcan1, Mehmet Ali Çetin1, Serdar Ensari1, Hüseyin Dere1.   

Abstract

BACKGROUND: Bell's palsy is the most frequent cause of unilateral facial paralysis. Inflammation is thought to play an important role in the pathogenesis of Bell's palsy. AIMS: Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are simple and inexpensive tests which are indicative of inflammation and can be calculated by all physicians. The aim of this study was to reveal correlations of Bell's palsy and degree of paralysis with NLR and PLR. STUDY
DESIGN: Case-control study.
METHODS: The retrospective study was performed January 2010 and December 2013. Ninety-nine patients diagnosed as Bell's palsy were included in the Bell's palsy group and ninety-nine healthy individuals with the same demographic characteristics as the Bell's palsy group were included in the control group. As a result of analyses, NLR and PLR were calculated.
RESULTS: The mean NLR was 4.37 in the Bell's palsy group and 1.89 in the control group with a statistically significant difference (p<0.001). The mean PLR was 137.5 in the Bell's palsy group and 113.75 in the control group with a statistically significant difference (p=0.008). No statistically significant relation was detected between the degree of facial paralysis and NLR and PLR.
CONCLUSION: The NLR and the PLR were significantly higher in patients with Bell's palsy. This is the first study to reveal a relation between Bell's palsy and PLR. NLR and PLR can be used as auxiliary parameters in the diagnosis of Bell's palsy.

Entities:  

Keywords:  Bell’s palsy; inflammation; lymphocytes; neutrophils; platelets

Year:  2015        PMID: 26167340      PMCID: PMC4432696          DOI: 10.5152/balkanmedj.2015.15456

Source DB:  PubMed          Journal:  Balkan Med J        ISSN: 2146-3123            Impact factor:   2.021


  12 in total

Review 1.  Bell's palsy and autoimmunity.

Authors:  A Greco; A Gallo; M Fusconi; C Marinelli; G F Macri; M de Vincentiis
Journal:  Autoimmun Rev       Date:  2012-06-08       Impact factor: 9.754

2.  Practical management of Bell's palsy.

Authors:  G B Hughes
Journal:  Otolaryngol Head Neck Surg       Date:  1990-06       Impact factor: 3.497

3.  The natural history of Bell's palsy.

Authors:  E Peitersen
Journal:  Am J Otol       Date:  1982-10

4.  Serum cytokine levels in Bell's palsy.

Authors:  Mustafa Yilmaz; Mehmet Tarakcioglu; Nurhayat Bayazit; Yildirim A Bayazit; Mustafa Namiduru; Muzaffer Kanlikama
Journal:  J Neurol Sci       Date:  2002-05-15       Impact factor: 3.181

Review 5.  Neutrophil to lymphocyte ratio and cardiovascular diseases: a review.

Authors:  Tariq Bhat; Sumaya Teli; Jharendra Rijal; Hilal Bhat; Muhammad Raza; Georges Khoueiry; Mustafain Meghani; Muhammad Akhtar; Thomas Costantino
Journal:  Expert Rev Cardiovasc Ther       Date:  2013-01

6.  Annualized incidence and spectrum of illness from an outbreak investigation of Bell's palsy.

Authors:  A M Morris; S L Deeks; M D Hill; G Midroni; W C Goldstein; T Mazzulli; R Davidson; S G Squires; T Marrie; A McGeer; D E Low
Journal:  Neuroepidemiology       Date:  2002 Sep-Oct       Impact factor: 3.282

7.  Neutrophil-to-lymphocyte ratio as a new, quick, and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss.

Authors:  Sahin Ulu; Memnune Sena Ulu; Abdulkadir Bucak; Ahmet Ahsen; Fatih Yucedag; Abdullah Aycicek
Journal:  Otol Neurotol       Date:  2013-10       Impact factor: 2.311

8.  A survey of facial paralysis: etiology and incidence.

Authors:  J N Bleicher; S Hamiel; J S Gengler; J Antimarino
Journal:  Ear Nose Throat J       Date:  1996-06       Impact factor: 1.697

9.  A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer.

Authors:  M J Proctor; D C McMillan; D S Morrison; C D Fletcher; P G Horgan; S J Clarke
Journal:  Br J Cancer       Date:  2012-07-24       Impact factor: 7.640

10.  Preoperative neutrophil-lymphocyte and platelet-lymphocyte ratios as independent predictors of cervical stromal involvement in surgically treated endometrioid adenocarcinoma.

Authors:  Dan Wang; Jia-Xin Yang; Dong-Yan Cao; Xi-Run Wan; Feng-Zhi Feng; Hui-Fang Huang; Keng Shen; Yang Xiang
Journal:  Onco Targets Ther       Date:  2013-03-16       Impact factor: 4.147

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  12 in total

1.  Letter to the Editor concerning "New Predictive Parameters of Bell's Palsy: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio".

Authors:  Elif Gülsüm Ümit
Journal:  Balkan Med J       Date:  2016-11-01       Impact factor: 2.021

2.  Diagnostic and prognostic value of procalcitonin levels in patients with Bell's palsy.

Authors:  Saffet Kilicaslan; Sinan Uluyol; Mehmet Hafit Gur; Ilker Burak Arslan; Ozlem Yagiz
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-02-19       Impact factor: 2.503

3.  Is C-reactive protein to albumin ratio an indicator of poor prognosis in Bell's palsy?

Authors:  Serkan Cayir; Omer Hizli; Serkan Kayabasi
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-10-16       Impact factor: 2.503

4.  Hematological Findings in Patients with Acute Peripheral Facial Palsy.

Authors:  Su Jin Kim; Ho Yun Lee
Journal:  J Int Adv Otol       Date:  2020-12       Impact factor: 1.017

5.  The relationship of high-frequency distortion product otoacoustic emission (DPOAE) values with hematological parameters in tinnitus patients.

Authors:  Akif Gunes; Elif Karali; Ahmet Ural; Fatih Ruzgar; Tugba Bayatkara
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-08-01       Impact factor: 2.503

6.  Hematologic parameters as predictive markers in pediatric Bell's palsy.

Authors:  Serkan Cayir; Cengizhan Kilicaslan
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-11-06       Impact factor: 2.503

7.  Efficacy of the Evaluation of Inflammatory Markers for the Reduction of Negative Appendectomy Rates.

Authors:  Fatih Mehmet Yazar; Aykut Urfalioglu; Murat Bakacak; Ömer Faruk Boran; Ertan Bülbüloğlu
Journal:  Indian J Surg       Date:  2016-10-18       Impact factor: 0.656

8.  Neutrophil to Lymphocyte Ratio, Platelet to Lymphocyte Ratio, Mean Platelet Volume and Red Cell Distribution Width Measures in Bells Palsy.

Authors:  Caner Sahin; Ceyhun Varım
Journal:  Open Access Maced J Med Sci       Date:  2017-01-09

Review 9.  The etiology of Bell's palsy: a review.

Authors:  Wenjuan Zhang; Lei Xu; Tingting Luo; Feng Wu; Bin Zhao; Xianqi Li
Journal:  J Neurol       Date:  2019-03-28       Impact factor: 4.849

10.  Diagnostic role of mean platelet volume and neutrophil to lymphocyte ratio in childhood brucellosis.

Authors:  Şefika Elmas Bozdemir; Yasemin Ay Altıntop; Salih Uytun; Humeyra Aslaner; Yasemin Altuner Torun
Journal:  Korean J Intern Med       Date:  2016-12-14       Impact factor: 2.884

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