Literature DB >> 26166619

Anxious moments for the protein tyrosine phosphatase PTP1B.

Navasona Krishnan1, Nicholas K Tonks2.   

Abstract

Chronic stress can lead to the development of anxiety and mood disorders. Thus, novel therapies for preventing adverse effects of stress are vitally important. Recently, the protein tyrosine phosphatase PTP1B was identified as a novel regulator of stress-induced anxiety. This opens up exciting opportunities to exploit PTP1B inhibitors as anxiolytics.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  anxiolytic therapy; endocannabinoid signaling; glutamate receptor; protein tyrosine phosphatase PTP1B; stress-induced anxiety; trodusquemine/MSI-1436

Mesh：

Substances：

Year:  2015        PMID： 26166619      PMCID： PMC4530058          DOI： 10.1016/j.tins.2015.06.006

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  15 in total

1.  Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases.

Authors:  Camilla Persson; Tobias Sjöblom; Arnoud Groen; Kai Kappert; Ulla Engström; Ulf Hellman; Carl-Henrik Heldin; Jeroen den Hertog; Arne Ostman
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-04       Impact factor: 11.205

2.  Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome".

Authors:  Robert Karisch; Minerva Fernandez; Paul Taylor; Carl Virtanen; Jonathan R St-Germain; Lily L Jin; Isaac S Harris; Jun Mori; Tak W Mak; Yotis A Senis; Arne Östman; Michael F Moran; Benjamin G Neel
Journal:  Cell       Date:  2011-09-02       Impact factor: 41.582

Review 3.  Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction.

Authors:  Nicholas K Tonks
Journal:  FEBS J       Date:  2013-01-17       Impact factor: 5.542

4.  The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling.

Authors:  Nihar R Pandey; Xun Zhou; Zhaohong Qin; Tariq Zaman; Mariana Gomez-Smith; Kianoosh Keyhanian; Hymie Anisman; Jean Michel Brunel; Alexandre F R Stewart; Hsiao-Huei Chen
Journal:  J Neurosci       Date:  2013-07-31       Impact factor: 6.167

5.  NADPH oxidase mediates depressive behavior induced by chronic stress in mice.

Authors:  Ji-Seon Seo; Jin-Young Park; Juli Choi; Tae-Kyung Kim; Joo-Hyun Shin; Ja-Kyeong Lee; Pyung-Lim Han
Journal:  J Neurosci       Date:  2012-07-11       Impact factor: 6.167

6.  Group I mGluRs coupled to G proteins are regulated by tyrosine kinase in dopamine neurons of the rat midbrain.

Authors:  A Tozzi; E Guatteo; L Caputi; G Bernardi; N B Mercuri
Journal:  J Neurophysiol       Date:  2001-06       Impact factor: 2.714

7.  Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons.

Authors:  L R Orlando; A W Dunah; D G Standaert; A B Young
Journal:  Neuropharmacology       Date:  2002-08       Impact factor: 5.250

Review 8.  Protein translation in synaptic plasticity: mGluR-LTD, Fragile X.

Authors:  Maggie W Waung; Kimberly M Huber
Journal:  Curr Opin Neurobiol       Date:  2009-05-04       Impact factor: 6.627

9.  Lmo4 in the basolateral complex of the amygdala modulates fear learning.

Authors:  Rajani Maiya; Viktor Kharazia; Amy W Lasek; Ulrike Heberlein
Journal:  PLoS One       Date:  2012-04-03       Impact factor: 3.240

10.  LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression.

Authors:  M E Montañez-Wiscovich; D D Seachrist; M D Landis; J Visvader; B Andersen; R A Keri
Journal:  Oncogene       Date:  2009-08-03       Impact factor: 9.867
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  4 in total

Review 1.  The metal face of protein tyrosine phosphatase 1B.

Authors:  Elisa Bellomo; Kshetrimayum Birla Singh; Alberto Massarotti; Christer Hogstrand; Wolfgang Maret
Journal:  Coord Chem Rev       Date:  2016-11-15       Impact factor: 22.315

2.  Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

Authors:  Kyojiro N Ikeda; Matthew Freeman
Journal:  J Biol Chem       Date:  2019-06-07       Impact factor: 5.157

Review 3.  From Marine Metabolites to the Drugs of the Future: Squalamine, Trodusquemine, Their Steroid and Triterpene Analogues.

Authors:  Oxana Kazakova; Gulnara Giniyatullina; Denis Babkov; Zdenek Wimmer
Journal:  Int J Mol Sci       Date:  2022-01-19       Impact factor: 5.923

4.  Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism.

Authors:  Ryan Limbocker; Benedetta Mannini; Francesco S Ruggeri; Roberta Cascella; Catherine K Xu; Michele Perni; Sean Chia; Serene W Chen; Johnny Habchi; Alessandra Bigi; Ryan P Kreiser; Aidan K Wright; J Alex Albright; Tadas Kartanas; Janet R Kumita; Nunilo Cremades; Michael Zasloff; Cristina Cecchi; Tuomas P J Knowles; Fabrizio Chiti; Michele Vendruscolo; Christopher M Dobson
Journal:  Commun Biol       Date:  2020-08-13
  4 in total

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