| Literature DB >> 26165402 |
Mohamed-Elamir F Hegazy1, Amira M Gamal-Eldeen2, Tarik A Mohamed1, Montaser A Alhammady3, Abuzeid A Hassanien4, Mohamed A Shreadah5, Ibrahim I Abdelgawad4, Eman M Elkady5, Paul W Paré6.
Abstract
Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2-9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.Entities:
Keywords: Nephthea sp.; breast cancer cell line MCF-7; cytotoxicity; terpenes
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Year: 2015 PMID： 26165402 DOI： 10.1080/14786419.2015.1055266
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861