Literature DB >> 26165120

[On the Enzymatic Activity of Albumin].

N V Goncharov, D A Belinskaia, A V Razygraev, A I Ukolov.   

Abstract

Albumin molecule, unlike molecules of many other plasma proteins, is not covered with carbohydrate shell. It plays a crucial role in maintaining of colloid osmotic pressure of the blood, and is able to bind and transport various endogenous and exogenous molecules. The enzymatic activity of albumin, the existence and the role of which most researchers are still skeptical to accept, is of the main interest to us. In this review, a history of the issue is traced, with particular attention to the esterase activity of albumin. The kinetic and thermodynamic characteristics of the interaction of albumin with some substrates are adduced, and possibility of albumin being attributed to certain groups of Enzyme Nomenclature is considered.

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Year:  2015        PMID: 26165120     DOI: 10.1134/s1068162015020041

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN: 0132-3423


  2 in total

1.  Serum Albumin Binding and Esterase Activity: Mechanistic Interactions with Organophosphates.

Authors:  Nikolay V Goncharov; Daria A Belinskaia; Vladimir I Shmurak; Maxim A Terpilowski; Richard O Jenkins; Pavel V Avdonin
Journal:  Molecules       Date:  2017-07-18       Impact factor: 4.411

2.  Integrative Role of Albumin: Evolutionary, Biochemical and Pathophysiological Aspects.

Authors:  D A Belinskaia; P A Voronina; N V Goncharov
Journal:  J Evol Biochem Physiol       Date:  2021-12-20       Impact factor: 0.444

  2 in total

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