Ignazio Roberto Zarbo1, Eleonora Minacapelli2, Monica Falautano2, Silvia Demontis3, Giovanni Carpentras3, Maura Pugliatti4. 1. Department of Biomedical Sciences, University of Sassari, Italy/Department of Clinical and Experimental Medicine, University of Sassari, Italy. 2. Department of Neurology, San Raffaele Scientific Institute and University, Milan, Italy. 3. Unit of Psychology, Sassari University Hospital (AOUSS), Sassari, Italy. 4. Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Italy maura.pugliatti@unife.it.
Abstract
BACKGROUND: Personality traits can affect health-related quality of life (HRQoL) in different disorders. In multiple sclerosis (MS), personality traits can determine patients' willingness to take on more risky treatment options, predispose to neuropsychiatric symptoms and affect coping strategies. OBJECTIVES: We investigated the role of personality traits as possible predictors of HRQoL in a large cohort of persons with MS (PwMS). METHODS: In total, 253 consecutively recruited PwMS were screened for intellectual deficits with Raven Colour Progressive Matrices (RCPM), state anxiety with STAI-X1 and major depression on a clinical basis. PwMS' self-perceived mental and physical health status was measured with the 36-Item Short Form Health Survey (SF-36), and the personality profile with the Eysenck Personality Questionnaire (EPQ-R). The correlation between HRQoL and personality traits was investigated by means of analysis of variance, adjusting for possible confounders. RESULTS: Of the 253 MS patients, 195 (F:M=2.75), aged 41.7±10.2 years were included in the analysis. The variance of SF-36 mental and physical composite score was largely explained by extraversion and neuroticism. CONCLUSIONS: Our data confirm that PwMS' HRQoL is largely influenced by personality traits, which may therefore act as predictors of perceived quality of life and should be included in clinical and experimental settings focusing on HRQoL.
BACKGROUND: Personality traits can affect health-related quality of life (HRQoL) in different disorders. In multiple sclerosis (MS), personality traits can determine patients' willingness to take on more risky treatment options, predispose to neuropsychiatric symptoms and affect coping strategies. OBJECTIVES: We investigated the role of personality traits as possible predictors of HRQoL in a large cohort of persons with MS (PwMS). METHODS: In total, 253 consecutively recruited PwMS were screened for intellectual deficits with Raven Colour Progressive Matrices (RCPM), state anxiety with STAI-X1 and major depression on a clinical basis. PwMS' self-perceived mental and physical health status was measured with the 36-Item Short Form Health Survey (SF-36), and the personality profile with the Eysenck Personality Questionnaire (EPQ-R). The correlation between HRQoL and personality traits was investigated by means of analysis of variance, adjusting for possible confounders. RESULTS: Of the 253 MS patients, 195 (F:M=2.75), aged 41.7±10.2 years were included in the analysis. The variance of SF-36 mental and physical composite score was largely explained by extraversion and neuroticism. CONCLUSIONS: Our data confirm that PwMS' HRQoL is largely influenced by personality traits, which may therefore act as predictors of perceived quality of life and should be included in clinical and experimental settings focusing on HRQoL.
Authors: Barbara Poletti; Laura Carelli; Annalisa Lafronza; Federica Solca; Andrea Faini; Andrea Ciammola; Monica Grobberio; Vanessa Raimondi; Rita Pezzati; Rita B Ardito; Vincenzo Silani Journal: Front Psychol Date: 2017-04-11
Authors: S Salhofer-Polanyi; F Friedrich; S Löffler; P S Rommer; A Gleiss; R Engelmaier; F Leutmezer; B Vyssoki Journal: BMC Psychiatry Date: 2018-05-23 Impact factor: 3.630