Babita Ghai1, Sameer Sethi2, Deepika Bansal3, Jagat Ram4. 1. Anesthesia Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India. 2. Anesthesia Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India. Electronic address: sameersethi29@gmail.com. 3. Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Mohali, Punjab, India. 4. Ophthalmology Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Abstract
STUDY OBJECTIVE: End-tidal concentration of sevoflurane for I-gel insertion in children has not been studied. This study was designed to determine the sevoflurane EC50 and EC95 for I-gel placement in children as compared with classic laryngeal mask airway (CLMA) placement. DESIGN: The design was a prospective, randomized controlled study. SETTINGS: The setting was single tertiary care center. PATIENTS: Pediatric subjects of either sex aged 1.5-8 years, weighing 10-20 kg having American Society of Anesthesiologists physical statusI/II of undergoing elective cataract surgery were included in the study. INTERVENTION: Induction and maintenance of anesthesia were achieved with sevoflurane and oxygen with preservation of spontaneous breathing. Children were randomly subjected to either I-gel size 2 (group I) or CLMA size 2 (group II) insertion. The target end-tidal sevoflurane concentration (ET SEVO) was maintained for 8-10 minutes before supraglottic airway device was inserted in both the groups. In the first child, the ET SEVO was kept at 2% and was increased or decreased by 0.2% in the next child depending on the previous child's response according to Dixon method. After each supraglottic airway device insertion, child was observed for 1 minute for any "movement" or "no movement." MEASUREMENTS: The measurements were EC50 and EC95 for I-gel and CLMA placement in children. MAIN RESULTS:EC50 and EC95 for group I were 0.94% (0.83%-1.06%) and 1.26% (1.12%-1.66%) and for group II were 1.9% (1.70%-2.1%) and 2.54% (2.24%-3.41%), respectively. CONCLUSION: I-gel insertion in children can be accomplished at nearly half ET SEVO (0.94%) of that required for CLMA insertion (1.9%).
RCT Entities:
STUDY OBJECTIVE: End-tidal concentration of sevoflurane for I-gel insertion in children has not been studied. This study was designed to determine the sevoflurane EC50 and EC95 for I-gel placement in children as compared with classic laryngeal mask airway (CLMA) placement. DESIGN: The design was a prospective, randomized controlled study. SETTINGS: The setting was single tertiary care center. PATIENTS: Pediatric subjects of either sex aged 1.5-8 years, weighing 10-20 kg having American Society of Anesthesiologists physical status I/II of undergoing elective cataract surgery were included in the study. INTERVENTION: Induction and maintenance of anesthesia were achieved with sevoflurane and oxygen with preservation of spontaneous breathing. Children were randomly subjected to either I-gel size 2 (group I) or CLMA size 2 (group II) insertion. The target end-tidal sevoflurane concentration (ET SEVO) was maintained for 8-10 minutes before supraglottic airway device was inserted in both the groups. In the first child, the ET SEVO was kept at 2% and was increased or decreased by 0.2% in the next child depending on the previous child's response according to Dixon method. After each supraglottic airway device insertion, child was observed for 1 minute for any "movement" or "no movement." MEASUREMENTS: The measurements were EC50 and EC95 for I-gel and CLMA placement in children. MAIN RESULTS: EC50 and EC95 for group I were 0.94% (0.83%-1.06%) and 1.26% (1.12%-1.66%) and for group II were 1.9% (1.70%-2.1%) and 2.54% (2.24%-3.41%), respectively. CONCLUSION: I-gel insertion in children can be accomplished at nearly half ET SEVO (0.94%) of that required for CLMA insertion (1.9%).