| Literature DB >> 26160450 |
Tiantian Zhu1, Xiaofei Ye, Tianyi Zhang, Zhiyong Lin, Wentao Shi, Xin Wei, Yuzhou Liu, Jia He.
Abstract
To investigate the association between alcohol consumption and multiple sclerosis risk, we performed a systematic literature search of PubMed, EmBase and Web of Science databases for all relevant articles regarding alcohol and multiple sclerosis. Our meta-analysis consisted of 10 studies, including nine case-controls and one cohort study. The odds ratios (OR) of the association between alcohol consumption and multiple sclerosis were 0.92 [95 % confidence interval (CI) 0.73-1.17] overall, 0.91 (95 % CI 0.39-2.41) for prospective study, and 0.92 (95 % CI 0.72-1.19) for retrospective studies. In addition, neither subgroup analyses nor sensitivity analyses showed a substantially change in the pooled OR and 95 % CI. Meta-analysis showed that there is no evidence that alcohol consumption is associated with an increased risk of multiple sclerosis. There may be a potential protective effect of alcohol consumption on MS incidence, however, this trend may not be obvious and should be validated by further research.Entities:
Mesh：
Year: 2015 PMID： 26160450 DOI： 10.1007/s10072-015-2326-7
Source DB: PubMed Journal: Neurol Sci ISSN： 1590-1874 Impact factor: 3.307