| Literature DB >> 26160157 |
Xian Yang1, Yu-Bo Zhang1, Zhong-Nan Wu1, Xiang-Qiang Zhang2, Jian-Wei Jiang2, Yao-Lan Li3, Guo-Cai Wang4.
Abstract
Six new prenylated acetophenone derivatives were isolated from the leaves of Acronychia oligophlebia. The chemical structures of them were elucidated by extensive analysis of spectroscopic data (IR, UV, HRESIMS, 1D and 2D NMR). The cytotoxic activity of the isolates was evaluated against MCF-7 cells. Among these compounds, 2 and 6 exhibited mild cytotoxic activity with IC50 values of 33.5 and 25.6 μM, respectively.Entities:
Keywords: Acronychia oligophlebia; Cytotoxic activity; Prenylated acetophenone
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Year: 2015 PMID： 26160157 DOI： 10.1016/j.fitote.2015.07.002
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882