UNLABELLED: Background/Aims: Laparoscopic cholecystectomy (LC) has become the gold standard for treating sy¬m¬ptomatic cholelithiasis. However, there are still some risk factors will lead to conversion to o¬p¬en cholecystectomy. The main aim of this meta-analysis is to evaluate preoperative risk fact¬o¬rs for converting laparoscopic to open cholecystectomy (LOC). METHODOLOGY: Evaluated risk factors of all clinical studies published from 1990 to 2012. All kinds of converting laparoscopic to open cholecystectomies were searched in the the Med-line, Embase, Science Citation Index, and PubMed databases. Random and fixed-effect models were used to aggregate the study endpoints and assess heterogeneity. The RevMan 5.2 was used for pooled estimates. RESULTS: Eleven NRCTs containing 14645 patients (940 in the LOC group and 13705 in the LC group) were included in the present meta-analysis. From the pooled analyses, age > 65 years (OR = 1.83, 95% CI (1.31, 2.45), P < 0.0001), male gender (OR = 2.23, 95% CI (1.59, 3.12), P < 0.00001), Diabetes Mellitus (OR = 1.89, 95% CI (1.30, 2.75), P = 0.0009), acute cholecystitis (OR = 3.37, 95% CI (1.83, 6.20), P < 0.0001), thickened gallbladder wall (OR = 6.04, 95% CI (4.11, 8.88), P < 0.00001) and previous upper abdominal surgery (OR = 4.43, 95% CI (2.17, 9.04), P < 0.00001) were independent predictive risk factors for conversion. Previous lower abdominal surgery, preoperative endoscopic retrograde cholangiopancreatography (ERCP) and the gallstone pancreatitis were not significantly associated with conversion (all P > 0.05). CONCLUSION: Our meta-analysis indicates that age > 65 years, male gender, acute cholecystitis, t¬hickened gallbladder wall, Diabetes Mellitus and previous upper abdominal surgery were sign¬i¬ficantly associated with increased risk of conversion. Evaluating these factors was useful for t¬h¬e doctors to make suitable operation scheme.
UNLABELLED: Background/Aims: Laparoscopic cholecystectomy (LC) has become the gold standard for treating sy¬m¬ptomatic cholelithiasis. However, there are still some risk factors will lead to conversion to o¬p¬en cholecystectomy. The main aim of this meta-analysis is to evaluate preoperative risk fact¬o¬rs for converting laparoscopic to open cholecystectomy (LOC). METHODOLOGY: Evaluated risk factors of all clinical studies published from 1990 to 2012. All kinds of converting laparoscopic to open cholecystectomies were searched in the the Med-line, Embase, Science Citation Index, and PubMed databases. Random and fixed-effect models were used to aggregate the study endpoints and assess heterogeneity. The RevMan 5.2 was used for pooled estimates. RESULTS: Eleven NRCTs containing 14645 patients (940 in the LOC group and 13705 in the LC group) were included in the present meta-analysis. From the pooled analyses, age > 65 years (OR = 1.83, 95% CI (1.31, 2.45), P < 0.0001), male gender (OR = 2.23, 95% CI (1.59, 3.12), P < 0.00001), Diabetes Mellitus (OR = 1.89, 95% CI (1.30, 2.75), P = 0.0009), acute cholecystitis (OR = 3.37, 95% CI (1.83, 6.20), P < 0.0001), thickened gallbladder wall (OR = 6.04, 95% CI (4.11, 8.88), P < 0.00001) and previous upper abdominal surgery (OR = 4.43, 95% CI (2.17, 9.04), P < 0.00001) were independent predictive risk factors for conversion. Previous lower abdominal surgery, preoperative endoscopic retrograde cholangiopancreatography (ERCP) and the gallstone pancreatitis were not significantly associated with conversion (all P > 0.05). CONCLUSION: Our meta-analysis indicates that age > 65 years, male gender, acute cholecystitis, t¬hickened gallbladder wall, Diabetes Mellitus and previous upper abdominal surgery were sign¬i¬ficantly associated with increased risk of conversion. Evaluating these factors was useful for t¬h¬e doctors to make suitable operation scheme.
Authors: Massimo Sartelli; Federico Coccolini; Yoram Kluger; Ervis Agastra; Fikri M Abu-Zidan; Ashraf El Sayed Abbas; Luca Ansaloni; Abdulrashid Kayode Adesunkanmi; Boyko Atanasov; Goran Augustin; Miklosh Bala; Oussama Baraket; Suman Baral; Walter L Biffl; Marja A Boermeester; Marco Ceresoli; Elisabetta Cerutti; Osvaldo Chiara; Enrico Cicuttin; Massimo Chiarugi; Raul Coimbra; Elif Colak; Daniela Corsi; Francesco Cortese; Yunfeng Cui; Dimitris Damaskos; Nicola De' Angelis; Samir Delibegovic; Zaza Demetrashvili; Belinda De Simone; Stijn W de Jonge; Sameer Dhingra; Stefano Di Bella; Francesco Di Marzo; Salomone Di Saverio; Agron Dogjani; Therese M Duane; Mushira Abdulaziz Enani; Paola Fugazzola; Joseph M Galante; Mahir Gachabayov; Wagih Ghnnam; George Gkiokas; Carlos Augusto Gomes; Ewen A Griffiths; Timothy C Hardcastle; Andreas Hecker; Torsten Herzog; Syed Mohammad Umar Kabir; Aleksandar Karamarkovic; Vladimir Khokha; Peter K Kim; Jae Il Kim; Andrew W Kirkpatrick; Victor Kong; Renol M Koshy; Igor A Kryvoruchko; Kenji Inaba; Arda Isik; Katia Iskandar; Rao Ivatury; Francesco M Labricciosa; Yeong Yeh Lee; Ari Leppäniemi; Andrey Litvin; Davide Luppi; Gustavo M Machain; Ronald V Maier; Athanasios Marinis; Cristina Marmorale; Sanjay Marwah; Cristian Mesina; Ernest E Moore; Frederick A Moore; Ionut Negoi; Iyiade Olaoye; Carlos A Ordoñez; Mouaqit Ouadii; Andrew B Peitzman; Gennaro Perrone; Manos Pikoulis; Tadeja Pintar; Giuseppe Pipitone; Mauro Podda; Kemal Raşa; Julival Ribeiro; Gabriel Rodrigues; Ines Rubio-Perez; Ibrahima Sall; Norio Sato; Robert G Sawyer; Helmut Segovia Lohse; Gabriele Sganga; Vishal G Shelat; Ian Stephens; Michael Sugrue; Antonio Tarasconi; Joel Noutakdie Tochie; Matti Tolonen; Gia Tomadze; Jan Ulrych; Andras Vereczkei; Bruno Viaggi; Chiara Gurioli; Claudio Casella; Leonardo Pagani; Gian Luca Baiocchi; Fausto Catena Journal: World J Emerg Surg Date: 2021-09-25 Impact factor: 5.469
Authors: D Serban; C Branescu; C Savlovschi; A P Purcărea; A El-Khatib; S A Balasescu; A Nica; A M Dascalu; G Vancea; S M Oprescu; C Tudor Journal: J Med Life Date: 2016 Oct-Dec
Authors: Massimo Sartelli; Alain Chichom-Mefire; Francesco M Labricciosa; Timothy Hardcastle; Fikri M Abu-Zidan; Abdulrashid K Adesunkanmi; Luca Ansaloni; Miklosh Bala; Zsolt J Balogh; Marcelo A Beltrán; Offir Ben-Ishay; Walter L Biffl; Arianna Birindelli; Miguel A Cainzos; Gianbattista Catalini; Marco Ceresoli; Asri Che Jusoh; Osvaldo Chiara; Federico Coccolini; Raul Coimbra; Francesco Cortese; Zaza Demetrashvili; Salomone Di Saverio; Jose J Diaz; Valery N Egiev; Paula Ferrada; Gustavo P Fraga; Wagih M Ghnnam; Jae Gil Lee; Carlos A Gomes; Andreas Hecker; Torsten Herzog; Jae Il Kim; Kenji Inaba; Arda Isik; Aleksandar Karamarkovic; Jeffry Kashuk; Vladimir Khokha; Andrew W Kirkpatrick; Yoram Kluger; Kaoru Koike; Victor Y Kong; Ari Leppaniemi; Gustavo M Machain; Ronald V Maier; Sanjay Marwah; Michael E McFarlane; Giulia Montori; Ernest E Moore; Ionut Negoi; Iyiade Olaoye; Abdelkarim H Omari; Carlos A Ordonez; Bruno M Pereira; Gerson A Pereira Júnior; Guntars Pupelis; Tarcisio Reis; Boris Sakakhushev; Norio Sato; Helmut A Segovia Lohse; Vishal G Shelat; Kjetil Søreide; Waldemar Uhl; Jan Ulrych; Harry Van Goor; George C Velmahos; Kuo-Ching Yuan; Imtiaz Wani; Dieter G Weber; Sanoop K Zachariah; Fausto Catena Journal: World J Emerg Surg Date: 2017-07-10 Impact factor: 5.469