Literature DB >> 2615711

[Experimental chemotherapy of alveolar hydatid disease. 12. The efficacy of drug forms of mebendazole and nocodazole with high bioavailability].

V I Dzhabarova, A E Dobrotvorskiĭ, A I Krotov.   

Abstract

New formulations have been designed to increase the efficacy and bioavailability of the oral drugs mebendazole and nocodazole and were tested in CBA mice. A considerable increase in efficacy was established for a solid disperse formulation of certain composition with a relatively lower toxicity than in aqueous suspensions of the drugs.

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Year:  1989        PMID: 2615711

Source DB:  PubMed          Journal:  Med Parazitol (Mosk)        ISSN: 0025-8326


  1 in total

1.  Enhanced bioavailability and cysticidal effect of three mebendazole-oil preparations in mice infected with secondary cysts of Echinococcus granulosus.

Authors:  Cong-shan Liu; Hao-bing Zhang; Bin Jiang; Jun-min Yao; Yi Tao; Jian Xue; Ai-dan Wen
Journal:  Parasitol Res       Date:  2012-06-04       Impact factor: 2.289

  1 in total

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