Literature DB >> 26155984

Isolated thymic Langerhans cell histiocytosis discovered on F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT).

Sophie Turpin1, Anne-Sophie Carret2, Josée Dubois3, Chantal Buteau4, Natalie Patey5.   

Abstract

The thymic infiltration in young patients with multisystemic Langerhans cell histiocytosis and its radiologic features are well known. However, isolated thymic disease has seldom been reported in the literature. We report the case of a 10-month-old child admitted for fever of unknown origin. Whole-body F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) was performed to identify a focus of infection. It demonstrated an unusual aspect of the thymus, which led to further investigation and revealed isolated infiltration of the thymus by Langerhans cell histiocytosis. The patient was treated accordingly and is now disease free. As evaluation of Langerhans cell histiocytosis patients with F-18 FDG PET/CT is becoming more frequent, it is important to be aware of the scintigraphical characteristics of thymic Langerhans cell histiocytosis.

Entities:  

Keywords:  Child; F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT); Langerhans cell histiocytosis; Thymus; Ultrasound

Mesh：

Substances：

Year:  2015        PMID： 26155984     DOI： 10.1007/s00247-015-3409-6

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN： 0301-0449


  7 in total

Review 1.  [The Langerhans cell histiocytosis with thymic localization as initial and exclusive place].

Authors:  J M Hernández Pérez; T Franquet Casas; S Rodríguez; A Giménez
Journal:  An Med Interna       Date:  2007-10

2.  Radiological features of thymic langerhans cell histiocytosis.

Authors:  Karoly Lakatos; Heidrun Herbrüggen; Ulrike Pötschger; Helmut Prosch; Milen Minkov
Journal:  Pediatr Blood Cancer       Date:  2013-06-29       Impact factor: 3.167

Review 3.  Whole-body MR imaging in children: principles, technique, current applications, and future directions.

Authors:  Govind B Chavhan; Paul S Babyn
Journal:  Radiographics       Date:  2011-10       Impact factor: 5.333

Review 4.  Pediatric FDG PET/CT: physiologic uptake, normal variants, and benign conditions.

Authors:  Amer Shammas; Ruth Lim; Martin Charron
Journal:  Radiographics       Date:  2009 Sep-Oct       Impact factor: 5.333

Review 5.  Extraosseous langerhans cell histiocytosis in children.

Authors:  Sabine Schmidt; Georg Eich; Anne Geoffray; Sylviane Hanquinet; Peter Waibel; Rainer Wolf; Igor Letovanec; Leonore Alamo-Maestre; Francois Gudinchet
Journal:  Radiographics       Date:  2008 May-Jun       Impact factor: 5.333

Review 6.  Multiple Langerhans cell nodules in an incidental thymectomy.

Authors:  Lea Novak; Claudia Y Castro; Catherine M Listinsky
Journal:  Arch Pathol Lab Med       Date:  2003-02       Impact factor: 5.534

7.  Diagnostic value of [(18)F]-FDG PET/CT in children with fever of unknown origin or unexplained signs of inflammation.

Authors:  Niklas Jasper; Jan Däbritz; Michael Frosch; Markus Loeffler; Matthias Weckesser; Dirk Foell
Journal:  Eur J Nucl Med Mol Imaging       Date:  2010-01       Impact factor: 9.236
  7 in total
  2 in total

Review 1.  18F-Fluorodeoxyglucose PET/CT in Langerhans cell histiocytosis: spectrum of manifestations.

Authors:  Krishan Kant Agarwal; Rachna Seth; Abhishek Behra; Manisha Jana; Rakesh Kumar
Journal:  Jpn J Radiol       Date:  2016-01-13       Impact factor: 2.374

2.  Pediatric thoracic mass lesions: Beyond the common.

Authors:  Gunes Orman; Prakash Masand; John Hicks; Thierry A G M Huisman; R Paul Guillerman
Journal:  Eur J Radiol Open       Date:  2020-06-11
  2 in total

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