Priya John1, Flemingson Lazarus2, Joann Pauline George3, Arul Selvam4, Munivenkatappa Lakshmaiah Venkatesh Prabhuji5. 1. Senior Lecturer, Mar Baselious Dental College , Kothamangalam, Kerala, India. 2. Former Professor and HOD, Department of Periodontology, Best Dental College , Madurai, India . 3. Professor, Department of Periodontics, Krishnadevaraya College of Dental Sciences , Bangalore, India . 4. Professor and HOD, Department of Microbiology, Krishnadevaraya College of Dental Sciences , Bangalore, India . 5. Professor and HOD, Department of Periodontics, Krishnadevaraya College of Dental Sciences , Bangalore, India .
Abstract
INTRODUCTION: PerioChip a bovine origin gelatine based CHX chip has shown beneficial effects in the management of Chronic Periodontitis. A new fish collagen based CHX chip similar to PerioChip is currently available; however this product has not been thoroughly researched. AIM: The aim of the present study was to evaluate the effectiveness of a new Piscean collagen-based controlled-release chlorhexidine chip (CHX chip) as an adjunctive therapy to scaling and root planing (SRP). SETTINGS AND DESIGN: The study was conducted as a randomised, split-mouth, controlled clinical trial at Krishnadevaraya College of Dental Sciences, Bangalore, India. MATERIALS AND METHODS: In a split-mouth study involving 20 sites in 10 patients with chronic periodontitis, control sites received scaling and root planing and test sites received scaling and root planing (SRP) and the intrapocket CHX chip placement as an adjunct. Subgingival plaque samples were collected from both control and test sites at baseline, 11 days and 11 weeks and the anaerobic colony count were assessed. Clinical parameters that were recorded at baseline and 11 weeks were gingival index, Plaque index, Probing pocket depth (PPD), and Clinical attachment level (CAL). Plaque index was recorded additionally at 11 days. RESULTS: In the test group there was a statistically significant reduction in the total anaerobic colony count, gingival index and plaque scores from baseline as compared to control sites at all time intervals. An additional 0.8mm reduction in mean probing pocket depth was noted in the test group. Gain in Clinical attachment level was comparable in both groups. CONCLUSION: The adjunctive use of the new collagen-based CHX chip yielded significant antimicrobial benefit accompanied by a reduction in probing depth and a clinical attachment level gain as compared to SRP alone. This suggests that it may be a useful treatment option of nonsurgical periodontal treatment of chronic periodontitis.
RCT Entities:
INTRODUCTION: PerioChip a bovine origin gelatine based CHX chip has shown beneficial effects in the management of Chronic Periodontitis. A new fish collagen based CHX chip similar to PerioChip is currently available; however this product has not been thoroughly researched. AIM: The aim of the present study was to evaluate the effectiveness of a new Piscean collagen-based controlled-release chlorhexidine chip (CHX chip) as an adjunctive therapy to scaling and root planing (SRP). SETTINGS AND DESIGN: The study was conducted as a randomised, split-mouth, controlled clinical trial at Krishnadevaraya College of Dental Sciences, Bangalore, India. MATERIALS AND METHODS: In a split-mouth study involving 20 sites in 10 patients with chronic periodontitis, control sites received scaling and root planing and test sites received scaling and root planing (SRP) and the intrapocket CHX chip placement as an adjunct. Subgingival plaque samples were collected from both control and test sites at baseline, 11 days and 11 weeks and the anaerobic colony count were assessed. Clinical parameters that were recorded at baseline and 11 weeks were gingival index, Plaque index, Probing pocket depth (PPD), and Clinical attachment level (CAL). Plaque index was recorded additionally at 11 days. RESULTS: In the test group there was a statistically significant reduction in the total anaerobic colony count, gingival index and plaque scores from baseline as compared to control sites at all time intervals. An additional 0.8mm reduction in mean probing pocket depth was noted in the test group. Gain in Clinical attachment level was comparable in both groups. CONCLUSION: The adjunctive use of the new collagen-based CHX chip yielded significant antimicrobial benefit accompanied by a reduction in probing depth and a clinical attachment level gain as compared to SRP alone. This suggests that it may be a useful treatment option of nonsurgical periodontal treatment of chronic periodontitis.
Authors: Giovanni E Salvi; Andrea Mombelli; Lisa Mayfield; Alexandra Rutar; Jean Suvan; Steven Garrett; Niklaus P Lang Journal: J Clin Periodontol Date: 2002-06 Impact factor: 8.728
Authors: Ivana Ferreira Gomes Rodrigues; Luciana Machion; Marcio Zafalon Casati; Francisco Humberto Nociti; Sergio de Toledo; Antonio Wilson Sallum; Enilson Antonio Sallum Journal: J Periodontol Date: 2007-04 Impact factor: 6.993
Authors: Cleber Davi Del Rei Daltro Rosa; Jéssica Marcela de Luna Gomes; Sandra Lúcia Dantas de Moraes; Cleidiel Aparecido Araujo Lemos; Tatiana Prosini da Fonte; João Pedro Justino de Oliveira Limirio; Eduardo Piza Pellizzer Journal: Saudi Dent J Date: 2020-11-11