Literature DB >> 26155535

Bilateral Infraorbital Nerve Block Versus Intravenous Pentazocine: A Comparative Study on Post-operative Pain Relief Following Cleft Lip Surgery.

Gurpreeti Grewal1, Kamakshi Garg1, Anju Grewal2.   

Abstract

BACKGROUND AND OBJECTIVES: Infra orbital nerve block is utilized for postoperative pain control in children undergoing cleft lip repair. This study was conducted to compare the effectiveness, advantages and disadvantages of infra orbital nerve block and opioids for postoperative pain relief following cheiloplasty.
MATERIALS AND METHODS: Sixty paediatric patients aged 3 months - 13 years undergoing cheiloplasty were selected by simple random sampling and were divided into two groups. All the children received standardized premedication with midazolam, were operated upon under general anaesthesia and the block was performed at the end of surgery before reversal. Group B patients were administered bilateral infra orbital nerve block with 0.25% Bupivacaine (upto 2 mg/kg). Group O patients received Pentazocine 0.5 mg / kg IV. Postoperatively, the heart rate and respiratory rates were recorded every 15 minutes for the first 60 minutes, half hourly till 4 hours and then at 12 and 24 hours. Behavioural assessment for pain / discomfort was done at intervals of ½, 1, 2, 3, 4, 12 and 24 hours. Need for supplementary analgesics and duration between the administration of block/opioid and the first dose of supplementary analgesics were noted. Side effects such as nausea and vomiting, pruritus, respiratory depression and bradycardia during each of these periods were noted.
RESULTS: Both the groups were comparable for age, sex, weight and operative time with no statistical difference. The mean duration of analgesia for infra orbital nerve block was 357.5 minutes i.e. 5 hours 58 minutes and that for opioid was 231 minutes i.e. 3 hours 51 minutes which was significantly lower than the hours of analgesia provided by the block. Further, at the 4th hour, 76.6% of the patients in Group O required supplementary analgesics, in contrast to only 16.6% in Group B. The incidence of nausea and vomiting and pruritus was also higher in Group O.
CONCLUSION: The results indicate that bilateral infra orbital nerve block provides effective analgesia in the postoperative period, lasting for 6 hours in comparison to 3½ - 4 hours following the administration of intravenous Pentazocine, with no major untoward effects.

Entities:  

Keywords:  Bupivacaine; Cheiloplasty; Postoperative analgesia

Year:  2015        PMID: 26155535      PMCID: PMC4484127          DOI: 10.7860/JCDR/2015/11953.5984

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  11 in total

1.  Bilateral infraorbital nerve block is superior to peri-incisional infiltration for analgesia after repair of cleft lip.

Authors:  K P Prabhu; J Wig; S Grewal
Journal:  Scand J Plast Reconstr Surg Hand Surg       Date:  1999-03

2.  Painless procedures in pediatrics pipe dream or a possibility.

Authors:  Venkat Shankar
Journal:  Indian Pediatr       Date:  2006-04       Impact factor: 1.411

3.  Analgesia and anesthesia in neonates.

Authors:  M Yaster
Journal:  J Pediatr       Date:  1987-09       Impact factor: 4.406

4.  Infraorbital nerve block in neonates for cleft lip repair: anatomical study and clinical application.

Authors:  A T Bösenberg; F W Kimble
Journal:  Br J Anaesth       Date:  1995-05       Impact factor: 9.166

5.  Analysis of behavioural and physiological parameters for the assessment of postoperative analgesic demand in newborns, infants and young children: a comprehensive report on seven consecutive studies.

Authors:  W Büttner; W Finke
Journal:  Paediatr Anaesth       Date:  2000       Impact factor: 2.556

6.  A comparison of bilateral infraorbital nerve block with intravenous fentanyl for analgesia following cleft lip repair in children.

Authors:  Arvind Rajamani; Vijaylakshmi Kamat; Vardaraja Ponnambalam Rajavel; Jyotsna Murthy; Syed Altaf Hussain
Journal:  Paediatr Anaesth       Date:  2007-02       Impact factor: 2.556

7.  Bilateral infraorbital block with 0.5% bupivacaine as post-operative analgesia following cheiloplasty in children.

Authors:  H F Nicodemus; M J Ferrer; V C Cristobal; L de Castro
Journal:  Scand J Plast Reconstr Surg Hand Surg       Date:  1991

8.  Infra-orbital nerve block for relief of postoperative pain following cleft lip surgery in infants.

Authors:  S Ahuja; A Datta; A Krishna; A Bhattacharya
Journal:  Anaesthesia       Date:  1994-05       Impact factor: 6.955

9.  Effects of preemptive analgesia on pain and cytokine production in the postoperative period.

Authors:  Benzion Beilin; Hanna Bessler; Eduard Mayburd; Genady Smirnov; Arie Dekel; Israel Yardeni; Yehuda Shavit
Journal:  Anesthesiology       Date:  2003-01       Impact factor: 7.892

10.  Comparison of Bupivacaine Alone and in Combination with Fentanyl or Pethidine for Bilateral infraorbital Nerve Block for Postoperative Analgesia in Paediatric Patients for Cleft Lip Repair: A Prospective Randomized Double Blind Study.

Authors:  Rajesh S Mane; C S Sanikop; Vithal K Dhulkhed; Tuhina Gupta
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2011-01
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  2 in total

Review 1.  Infraorbital nerve block for postoperative pain following cleft lip repair in children.

Authors:  Gustavo Feriani; Eric Hatanaka; Maria R Torloni; Edina M K da Silva
Journal:  Cochrane Database Syst Rev       Date:  2016-04-13

2.  Effect of bilateral infraorbital nerve block on intraoperative anesthetic requirements, hemodynamics, glycemic levels, and extubation in infants undergoing cheiloplasty under general anesthesia.

Authors:  Sunil Rajan; Jacob Mathew; Lakshmi Kumar
Journal:  J Dent Anesth Pain Med       Date:  2021-03-31
  2 in total

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