INTRODUCTION: The number of elderly patients with chronic kidney disease increases progressively, challenging the allocation algorithms in a scenario of organ shortage for transplantation. OBJECTIVE: To evaluate the impact of age on patient and graft survival. METHODS: Evolution of all 366 patients greater than 60 years transplanted between 1998 and 2010 was analyzed versus a control group of 366 younger patients matched for gender, type of donor (living or deceased) and year of transplantation. RESULTS: Diabetes mellitus (HR 1.8; IC 1.2-2.6; p = 0,003) and prioritization (HR 2.9; IC 1.2-2.6; p < 0,001), but not age, were independent factors for kidney graft loss. CONCLUSION: Advanced age was not related to negative outcomes after kidney transplantation, after excluding recipient death as a cause of allograft loss. Higher mortality rate in this group was associated to a higher frequency of comorbidities, especially diabetes mellitus.
INTRODUCTION: The number of elderly patients with chronic kidney disease increases progressively, challenging the allocation algorithms in a scenario of organ shortage for transplantation. OBJECTIVE: To evaluate the impact of age on patient and graft survival. METHODS: Evolution of all 366 patients greater than 60 years transplanted between 1998 and 2010 was analyzed versus a control group of 366 younger patients matched for gender, type of donor (living or deceased) and year of transplantation. RESULTS:Diabetes mellitus (HR 1.8; IC 1.2-2.6; p = 0,003) and prioritization (HR 2.9; IC 1.2-2.6; p < 0,001), but not age, were independent factors for kidney graft loss. CONCLUSION: Advanced age was not related to negative outcomes after kidney transplantation, after excluding recipient death as a cause of allograft loss. Higher mortality rate in this group was associated to a higher frequency of comorbidities, especially diabetes mellitus.
Authors: Ubiracé Fernando Elihimas Júnior; Jamila Pinho Couto; Wallace Pereira; Michel Pompeu Barros de Oliveira Sá; Eduardo Eriko Tenório de França; Filipe Carrilho Aguiar; Diogo Buarque Cordeiro Cabral; Saulo Barbosa Vasconcelos Alencar; Saulo José da Costa Feitosa; Thais Oliveira Claizoni Dos Santos; Helen Conceição Dos Santos Elihimas; Emilly Pereira Alves; Marcio José de Carvalho Lima; Frederico Castelo Branco Cavalcanti; Paulo Adriano Schwingel Journal: J Aging Res Date: 2020-08-19