Literature DB >> 26150630

Novel surgical management of a laryngeal granular cell tumour.

Charlotte Jane McIntyre1, John Lee Y Allen2, Harry Powell1, Guri Sandhu1.   

Abstract

Granular cell tumour (GCT) is a rare benign tumour occurring, most commonly, in the head and neck. Multiple tumours occur in 5-16% of patients. These tumours are chemo-radio-resistant and have high recurrence rates despite their benign histopathological features. Traditional management, depending on access, involves total tumour resection with wide margins due to the high rates of recurrence with incomplete resection. We present a patient with two synchronous GCTs of their upper airway: in the larynx and the trachea. Complete excision of the supraglottic lesion would have rendered the patient's larynx incompetent. Therefore, after multidisciplinary team (MDT) discussion, and following a discussion with the patient regarding the risks and benefits, a novel surgical management approach was agreed. Subtotal CO2 laser excision of the upper GCT was performed enabling functional organ preservation. A subsequent procedure was required when the patient became symptomatic due to tumour recurrence. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26150630      PMCID: PMC4493229          DOI: 10.1136/bcr-2015-209476

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

1.  Paediatric granular cell tumour of the larynx: case report of laser resection with frozen section.

Authors:  C Holton; H E Cruickshank; A S High; K Maclennan; Z G G Makura
Journal:  J Laryngol Otol       Date:  2007-01-25       Impact factor: 1.469

2.  The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin.

Authors:  Simona Gurzu; Diana Ciortea; Adrian Tamasi; Mircea Golea; Andrea Bodi; Danut Ioan Sahlean; Attila Kovecsi; Ioan Jung
Journal:  Arch Dermatol Res       Date:  2014-09-28       Impact factor: 3.017

3.  Gastric Abrikosoff tumor (granular cell tumor): case report.

Authors:  D Pertile; S Scabini; E Romairone; R Scordamaglia; E Rimini; V Ferrando
Journal:  G Chir       Date:  2010-10

4.  Laryngeal granular cell tumor.

Authors:  Carlos Arevalo; Bella Maly; Ron Eliashar; Menachem Gross
Journal:  J Voice       Date:  2006-11-28       Impact factor: 2.009

5.  Atypical granular cell tumor-apropos of a case with indeterminate malignant potential.

Authors:  Anne Mahoney; Amit Garg; Deon Wolpowitz; Meera Mahalingam
Journal:  Am J Dermatopathol       Date:  2010-06       Impact factor: 1.533

Review 6.  Granular cell tumors of the larynx: diagnosis and management.

Authors:  Jeremy B White; Robert Glade; Christopher Thomas Rossi; Steven Bielamowicz
Journal:  J Voice       Date:  2008-03-17       Impact factor: 2.009

7.  Granular cell tumor on larynx.

Authors:  Jun-Hee Park; Nam-Yong Do; Sung-Il Cho; Ji-Yun Choi
Journal:  Clin Exp Otorhinolaryngol       Date:  2010-03-30       Impact factor: 3.372

8.  Childhood granular cell tumors: two case reports.

Authors:  N Leboulanger; I Rouillon; J F Papon; P Josset; G Roger; E N Garabédian
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2007-12-20       Impact factor: 1.675

Review 9.  Granular cell tumor of the larynx in children: a case report.

Authors:  Wanessa Alessandra Ruiz Scala; Alessandro Murano Ferre Fernandes; André de C Duprat; Henrique O Olival Costa
Journal:  Braz J Otorhinolaryngol       Date:  2008 Sep-Oct
  9 in total
  1 in total

1.  Epiglottic granular cell tumour: a case report and literature review.

Authors:  Sarah Bouayyad; Jen Ong; Houda Bouayyad; Heerani Woodun
Journal:  J Surg Case Rep       Date:  2020-02-19
  1 in total

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